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NFKB2 抗体 (Ser871)

NFKB2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197572
发货至: 中国
  • 抗原 See all NFKB2 抗体
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    抗原表位
    • 16
    • 14
    • 13
    • 13
    • 11
    • 11
    • 6
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    Ser871
    适用
    • 135
    • 95
    • 60
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 134
    • 7
    克隆类型
    • 123
    • 17
    • 1
    多克隆
    标记
    • 79
    • 12
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    • 5
    • 5
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    • 5
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    • 1
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    This NFKB2 antibody is un-conjugated
    应用范围
    • 86
    • 48
    • 41
    • 27
    • 22
    • 16
    • 16
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    • 11
    • 3
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    NFκB-p100/p52 antibody detects endogenous levels of total NFκB-p100/p52 protein.
    纯化方法
    Affinity chromatography
    免疫原
    The antiserum was produced against synthesized non-phosphopeptide derived from human NFkappaB-p100/p52 around the phosphorylation site of serine 871 (S-Q-SP-V-E).
    Top Product
    Discover our top product NFKB2 Primary Antibody
  • 应用备注
    Western Blot: 1: 500approx. 1: 1000. Immunohistochemistry: 1: 50approx. 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    别名
    NFKB2 / NF-kappa-B p100/p52 (NFKB2 产品)
    别名
    NF-kappaB2 antibody, lyt antibody, p49 antibody, p49/p100 antibody, p50B antibody, p52 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 antibody, Nfkb2 antibody
    背景
    NFkB is formed through the association of multiple subunits, either as a homodimer or heterodimer. Subunits have been identified as p50 (NFkB1), p65 (RelA), c-Rel, RelB and p52 (NFkB2). The classic NFkB form exists as a p50-p65 heterodimer and predominates in many cell types. Many of the possible combinatorial forms of homo- and heterodimers have been identified and growing evidence indicates that different forms of NFkB have different functions in cells. Interestingly, both the p50 and p52 subunits are derived from the precursor proteins p105 and p100 respectively, that each contain multiple copies of the so called ankyrin repeat at their C termini. Nuclear translocation of NFkB is confirmed by the use of electrophorectic mobility shift assays or by immunoblotting with nuclear extracts. The subunit composition of NFkB is confirmed by the use of antibodies that "supershift" the DNA/protein complex.Synonyms: DNA-binding factor KBF2, H2TF1, KBF2, LYT10, Lymphocyte translocation chromosome 10, NF kappa B, NF-kB p100, NF-kB p52, Nuclear factor NF-kappa-B p100 subunit, Oncogene Lyt-10
    基因ID
    4791
    NCBI登录号
    NP_001070961
    UniProt
    Q00653
    途径
    Toll-Like Receptors Cascades
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