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Connexin 43/GJA1 抗体 (pSer367, pSer368)

GJA1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197018
发货至: 中国
  • 抗原 See all Connexin 43/GJA1 (GJA1) 抗体
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    抗原表位
    • 21
    • 16
    • 15
    • 12
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
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    • 2
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    • 1
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    • 1
    • 1
    • 1
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    pSer367, pSer368
    适用
    • 135
    • 93
    • 91
    • 33
    • 12
    • 12
    • 11
    • 10
    • 10
    • 8
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 130
    • 8
    • 4
    • 1
    克隆类型
    • 134
    • 8
    多克隆
    标记
    • 83
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Connexin 43/GJA1 antibody is un-conjugated
    应用范围
    • 98
    • 54
    • 48
    • 29
    • 21
    • 16
    • 13
    • 13
    • 11
    • 9
    • 8
    • 5
    • 3
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    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.This antibody detects endogenous levels of Connexin43 only when phosphorylated at serine 367.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    The antiserum was produced against synthesized phosphopeptide derived from human Connexin-43 around the phosphorylation site of serine 367 (R-A-SP-S-R).
    Top Product
    Discover our top product GJA1 Primary Antibody
  • 应用备注
    Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/100 (Suitable for Paraffin Embedded Sections).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS(without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    别名
    GJA1 / Cx43 (GJA1 产品)
    别名
    AVSD3 antibody, CX43 antibody, DFNB38 antibody, GJAL antibody, HLHS1 antibody, HSS antibody, ODDD antibody, Cx43 antibody, AU042049 antibody, AW546267 antibody, Cnx43 antibody, Cx43alpha1 antibody, Gja-1 antibody, Npm1 antibody, connexin43 antibody, cx43a1 antibody, gja1 antibody, zfCx43.3 antibody, connexin 43 antibody, gja1-A antibody, cx43 antibody, gjal antibody, oddd antibody, dfnb38 antibody, gap junction protein alpha 1 antibody, gap junction protein, alpha 1 antibody, connexin 43 antibody, gap junction protein alpha 1 L homeolog antibody, CONNEXIN 43 protein antibody, GJA1 antibody, Gja1 antibody, cx43 antibody, gja1.L antibody, gja1 antibody, CONNEXIN 43 antibody
    背景
    GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5.Synonyms: Connexin-43, GJAL, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein
    基因ID
    2697
    NCBI登录号
    NP_000156
    UniProt
    P17302
    途径
    MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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