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IRAK1 抗体 (AA 618-712)

IRAK1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN1885516
发货至: 中国
  • 抗原 See all IRAK1 抗体
    IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
    抗原表位
    • 31
    • 19
    • 18
    • 16
    • 10
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 618-712
    适用
    • 143
    • 85
    • 62
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 142
    • 13
    • 2
    小鼠
    克隆类型
    • 145
    • 12
    单克隆
    标记
    • 62
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRAK1 antibody is un-conjugated
    应用范围
    • 114
    • 69
    • 65
    • 56
    • 52
    • 25
    • 17
    • 13
    • 13
    • 11
    • 7
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunoaffinity chromotography purified IgG
    免疫原
    Raised against a recombinant protein corresponding to amino acids 618 - 712 of human IRAK.
    Top Product
    Discover our top product IRAK1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    -20 °C
    储存方法
    Can be stored at -20 °C, stable for one year.
    有效期
    12 months
  • 抗原
    IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
    别名
    IRAK (IRAK1 产品)
    别名
    IRAK1 antibody, IRAK antibody, pelle antibody, AA408924 antibody, IRAK-1 antibody, IRAK1-S antibody, Il1rak antibody, Plpk antibody, mPLK antibody, RGD1563841 antibody, interleukin 1 receptor associated kinase 1 antibody, interleukin-1 receptor-associated kinase 1 antibody, IRAK1 antibody, irak1 antibody, Irak1 antibody
    背景
    Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses.NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS.A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently.IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response.IRAK mediates a signaling cascade leading to NF-kappaB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
    Synonyms: IRAK (8F1A7),IL-1-Receptor Associated Kinase
    途径
    NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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