MGMT 抗体
(5 references)-
- 抗原 See all MGMT 抗体
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MGMT antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- Purified His-tagged MGMT protein was used to produced this monoclonal antibody.
- 克隆位点
- 888CT22-2-4
- 亚型
- IgG1
- Top Product
- Discover our top product MGMT Primary Antibody
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anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 32-210) antibody
MGMT 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1A11F8 unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 101-207) antibodyMGMT 适用: 大鼠 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (N-Term) antibodyMGMT 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 156-182) antibodyMGMT 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) antibodyMGMT 适用: 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 156-182), (C-Term) antibodyMGMT 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19082 unconjugated
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- 应用备注
- IF: 1:25. WB: 1:1000. IHC: 1:100. IHC-P: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "The role of tyrosine-158 in O6-alkylguanine-DNA alkyltransferase activity." in: Carcinogenesis, Vol. 16, Issue 7, pp. 1637-42, (1995) (PubMed).
: "Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 2, pp. 686-90, (1990) (PubMed).
: "cDNA cloning and chromosomal assignment of the human O6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cells." in: The Journal of biological chemistry, Vol. 265, Issue 16, pp. 9563-9, (1990) (PubMed).
: "Purification, structure, and biochemical properties of human O6-methylguanine-DNA methyltransferase." in: The Journal of biological chemistry, Vol. 265, Issue 25, pp. 14754-62, (1990) (PubMed).
: "Expression and cloning of complementary DNA for a human enzyme that repairs O6-methylguanine in DNA." in: Journal of molecular biology, Vol. 213, Issue 4, pp. 739-47, (1990) (PubMed).
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: "The role of tyrosine-158 in O6-alkylguanine-DNA alkyltransferase activity." in: Carcinogenesis, Vol. 16, Issue 7, pp. 1637-42, (1995) (PubMed).
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- 抗原
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- 别名
- MGMT (MGMT 产品)
- 别名
- AGT antibody, AI267024 antibody, Agat antibody, O-6-methylguanine-DNA methyltransferase antibody, MGMT antibody, Mgmt antibody
- 背景
- Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
- 分子量
- 21646
- UniProt
- P16455
- 途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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