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MGMT 抗体 (AA 101-207)

This 兔 多克隆 antibody specifically detects MGMT in WB, IHC (p), IHC (fro), IF (cc) 和 IF (p). It exhibits reactivity toward 人.It has been mentioned in 1 publication
产品编号 ABIN730768
发货至: 中国
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Quick Overview for MGMT 抗体 (AA 101-207) (ABIN730768)

抗原

See all MGMT 抗体
MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

适用

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人

宿主

  • 113
  • 22
兔

克隆类型

  • 69
  • 66
多克隆

标记

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This MGMT antibody is un-conjugated

应用范围

  • 93
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 16
    • 12
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    • 1
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    AA 101-207

    原理

    MGMT Polyclonal Antibody

    交叉反应

    大鼠

    预测反应

    Human,Mouse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MGMT

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: "Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive." in: Journal of Alzheimer's disease : JAD, (2014) (PubMed).

  • 抗原

    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

    别名

    MGMT

    背景

    Synonyms: Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase

    Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    基因ID

    4255

    UniProt

    P16455

    途径

    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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