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MGMT 抗体 (C-Term)

MGMT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6972348
发货至: 中国
  • 抗原 See all MGMT 抗体
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    抗原表位
    • 17
    • 13
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 73
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 69
    • 11
    克隆类型
    • 61
    • 19
    多克隆
    标记
    • 45
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MGMT antibody is un-conjugated
    应用范围
    • 55
    • 33
    • 22
    • 22
    • 14
    • 13
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    产品特性
    MGMT (O-6 methylguanine DNA methyltransferase) is an enzyme involved in DNA damage repair. MGMT transfers methyl groups from O-6 methylguanine methylated DNA, and other methylated adducts, to a cysteine residue in itself, thus reversing DNA damage caused by alkylation. This is a suicide reaction as the enzyme is irreversibly inactivated. MGMT helps prevent DNA alkylation events from causing mutations. It also contributes to resistance to chemotherapy in cancer patients being treated with alkylating drugs. MGMT antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.
    纯化方法
    Affinity Purified
    免疫原
    This MGMT antibody was raised against a peptide derived from the C-terminal region of human MGMT.
    亚型
    IgG
    Top Product
    Discover our top product MGMT Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    别名
    MGMT (MGMT 产品)
    别名
    AGT antibody, AI267024 antibody, Agat antibody, O-6-methylguanine-DNA methyltransferase antibody, MGMT antibody, Mgmt antibody
    分子量
    28 kDa
    NCBI登录号
    NP_002403
    途径
    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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