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eIF4EBP1 抗体
EIF4EBP1
适用: 人
WB, IHC, ELISA
宿主: 小鼠
Monoclonal
unconjugated
eIF4EBP1抗体详情
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抗原
See all eIF4EBP1 (EIF4EBP1) 抗体
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
适用
All reactivities for eIF4EBP1 抗体
人
宿主
All hosts for eIF4EBP1 抗体
小鼠
克隆类型
All clonalities for eIF4EBP1 抗体
单克隆
标记
All conjugates for eIF4EBP1 抗体
This eIF4EBP1 antibody is un-conjugated
应用范围
All applications for eIF4EBP1 抗体
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
纯化方法
Purified antibody
免疫原
Purified recombinant fragment of 4EBP1 expressed in E. coli.
亚型
IgG1
Top Product
Discover our top product EIF4EBP1 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1.0 mg/mL
缓冲液
PBS containing 0.03 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
eIF4EBP1目标详情
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抗原
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
别名
4E-BP1 (EIF4EBP1 产品 )
别名
4E-BP1 antibody, 4EBP1 antibody, BP-1 antibody, PHAS-I antibody, 4e-bp1 antibody, AA959816 antibody, 153432_at antibody, 43-BP antibody, 4E-BP antibody, 4EBP antibody, 4e-bp antibody, 4eBP antibody, 4ebp antibody, BcDNA.HL08053 antibody, BcDNA:HL08053 antibody, CG8846 antibody, CT8705 antibody, Dm 4E-BP antibody, Dmel\\CG8846 antibody, Phas1 antibody, Thor/EIF4EBP antibody, anon-WO0172774.158 antibody, d4E-BP antibody, d4E-BP1 antibody, d4EBP antibody, d4e-bp antibody, d4eBP antibody, dthor antibody, eIF4E-BP antibody, l(2)06270 antibody, l(2)k07736 antibody, l(2)k13517 antibody, pp20 antibody, thor antibody, EIF4EBP1 antibody, fc04h09 antibody, wu:fc04h09 antibody, zgc:64137 antibody, eukaryotic translation initiation factor 4E binding protein 1 antibody, CG8846 gene product from transcript CG8846-RA antibody, EIF4EBP1 antibody, Eif4ebp1 antibody, Thor antibody, eif4ebp1 antibody
背景
4E-BP1 (eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I ,which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa).Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1.Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while (24kDa), the phosphorylated form will not.Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64.Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
基因ID
1978
UniProt
Q13541
途径
MAPK Pathway , PI3K-Akt Signaling , RTK signaling , AMPK Signaling , Regulation of Cell Size , BCR Signaling
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