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MTOR 抗体 (pSer2448)

mTOR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1531910
发货至: 中国
  • 抗原 See all MTOR (mTOR) 抗体
    MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
    抗原表位
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    AA 2415-2464, pSer2448
    适用
    • 211
    • 139
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    人, 小鼠, 大鼠
    宿主
    • 192
    • 15
    • 2
    • 2
    克隆类型
    • 172
    • 38
    多克隆
    标记
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    This MTOR antibody is un-conjugated
    应用范围
    • 146
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性

    mTOR (Phospho-Ser2448) Antibody detects endogenous levels of mTOR only when phosphorylated at Ser2448.

    PhosphorylationH:S2448 M:S2448 R:S2448

    纯化方法
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    纯度
    > 95 %
    免疫原
    The antiserum was produced against synthesized peptide derived from human mTOR around the phosphorylation site of Ser2448.
    亚型
    IgG
    Top Product
    Discover our top product mTOR Primary Antibody
  • 应用备注
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000
    说明

    Unigene-Number: Hs.338207 (NCBI Gene Symbol: MTOR)

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable at -20°C for at least 1 year.
    有效期
    12 months
  • Luo, Yoneda, Ohmori, Sasaki, Shimbo, Eto, Kato, Miyano, Kobayashi, Sasahira, Chihara, Kuniyasu: "Cancer usurps skeletal muscle as an energy repository." in: Cancer research, Vol. 74, Issue 1, pp. 330-40, (2014) (PubMed).

  • 抗原
    MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
    别名
    mTOR (mTOR 产品)
    别名
    FRAP1 antibody, FRAP antibody, FRAP2 antibody, RAFT1 antibody, RAPT1 antibody, 2610315D21Rik antibody, AI327068 antibody, Frap1 antibody, flat antibody, frap1 antibody, tor antibody, wu:fc22h08 antibody, mechanistic target of rapamycin kinase antibody, mechanistic target of rapamycin antibody, mechanistic target of rapamycin (serine/threonine kinase) antibody, MTOR antibody, Mtor antibody, mtor antibody
    背景

    Synonyms: FRAP, FRAP1, FRAP2, RAFT1, Rapamycin target protein, kinase mTOR

    NCBI Gene Symbol: MTOR

    分子量
    288 kDa
    基因ID
    2475
    OMIM
    601231
    UniProt
    P42345
    途径
    PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
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