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MTOR 产品

(Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008].

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Featured MTOR Categories

MTOR 抗体

High quality antibodies with extensive validation data.

MTOR ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MTOR 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MTOR 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (9)
  • (3)
  • (1)
Cat. No. ABIN676403
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (10)
Cat. No. ABIN6144169
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IHC (p), IP, ICC, ChIP
Validations
  • (5)
  • (15)
Cat. No. ABIN2855088
Quantity 100 μL
Datasheet Datasheet

Recommended MTOR ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968516
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968515
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968514
Quantity 96 tests
Datasheet Datasheet

Recommended MTOR 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (2)
Cat. No. ABIN2726555
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311601
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7412476
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MTOR Products

Du, Li, He, Li, Yang, Zou, Yang, Zhang, Xing: "Downregulation of the ubiquitin ligase KBTBD8 prevented epithelial ovarian cancer progression." in: Molecular medicine (Cambridge, Mass.), Vol. 26, Issue 1, pp. 96, (2021) (PubMed).

Zhou, Guo, Huang, Yu, Xu, Long: "Linc-ROR promotes the progression of breast cancer and decreases the sensitivity to rapamycin through miR-194-3p targeting MECP2." in: Molecular oncology, Vol. 14, Issue 9, pp. 2231-2250, (2021) (PubMed).

Ding, Xi, Zhong, Chen, Zhao, Zhang, Fang: "Cynaropicrin Induces Cell Cycle Arrest and Apoptosis by Inhibiting PKM2 to Cause DNA Damage and Mitochondrial Fission in A549 Cells." in: Journal of agricultural and food chemistry, Vol. 69, Issue 45, pp. 13557-13567, (2021) (PubMed).

Wang, Cao, Shu, Zhu, Peng, Ran, Wu, Luo, Zuo, Luo, Zhou, Shi, Weng, Huang, He, Fan: "Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes." in: Journal of cellular and molecular medicine, Vol. 24, Issue 2, pp. 1399-1412, (2020) (PubMed).

Cheung, Hsu, Lin, Chen, Wang, Huang, Juan: "ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 75, (2020) (PubMed).

Zheng, Yang, Wang, Zhang, Wang, Li, Wang, Wang, Yang: "HDAC6, modulated by miR-206, promotes endometrial cancer progression through the PTEN/AKT/mTOR pathway." in: Scientific reports, Vol. 10, Issue 1, pp. 3576, (2020) (PubMed).

Gugel, Ebner, Grimm, Czemmel, Paulsen, Hagel, Tatagiba, Nahnsen, Tabatabai: "Contribution of mTOR and PTEN to Radioresistance in Sporadic and NF2-Associated Vestibular Schwannomas: A Microarray and Pathway Analysis." in: Cancers, Vol. 12, Issue 1, (2020) (PubMed).

Guo, Wang, Li, Liang, Li, Gao, He: "Metformin Protects Against Spinal Cord Injury by Regulating Autophagy via the mTOR Signaling Pathway." in: Neurochemical research, Vol. 43, Issue 5, pp. 1111-1117, (2019) (PubMed).

Chiavari, Ciotti, Navarra, Lisi: "Pro-Inflammatory Activation of A New Immortalized Human Microglia Cell Line." in: Brain sciences, Vol. 9, Issue 5, (2019) (PubMed).

Lisi, Ciotti, Chiavari, Pizzoferrato, Mangiola, Kalinin, Feinstein, Navarra: "Phospho-mTOR expression in human glioblastoma microglia-macrophage cells." in: Neurochemistry international, Vol. 129, pp. 104485, (2019) (PubMed).

Synonyms and alternative names related to MTOR

mechanistic target of rapamycin kinase (MTOR), mechanistic target of rapamycin (MTOR), mechanistic target of rapamycin (serine/threonine kinase) (Mtor), mechanistic target of rapamycin kinase (Mtor), mechanistic target of rapamycin kinase (mtor), 2610315D21Rik, AI327068, flat, FRAP, FRAP1, Frap1, frap1, FRAP2, RAFT1, RAPT1, tor, wu:fc22h08

Protein level used designations for MTOR

  • FK506 binding protein 12-rapamycin associated protein 1
  • FK506 binding protein 12-rapamycin associated protein 2
  • FK506-binding protein 12-rapamycin complex-associated protein 1
  • FKBP-rapamycin associated protein
  • FKBP12-rapamycin complex-associated protein 1
  • mammalian target of rapamycin
  • rapamycin and FKBP12 target 1
  • rapamycin associated protein FRAP2
  • rapamycin target protein 1
  • serine/threonine-protein kinase mTOR
  • FKBP-rapamycin associated protein (FRAP)
  • FKBP-rapamycin-associated protein FRAP
  • FKBP12-rapamycin complex-associated protein
  • angiopoietin-like factor CDT6
  • RAPT1
  • rapamycin and FKBP12 target-1 protein
  • target of rapamycin
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