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CD59 抗体

CD59 适用: 人, Pig FACS, Func 宿主: 小鼠 Monoclonal MEM-129 unconjugated
产品编号 ABIN120694
发货至: 中国
  • 抗原 See all CD59 抗体
    CD59
    适用
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    人, Pig
    宿主
    • 90
    • 69
    • 6
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    小鼠
    克隆类型
    • 97
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    • 1
    单克隆
    标记
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    This CD59 antibody is un-conjugated
    应用范围
    • 101
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    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    The antibody MEM-129 reacts with CD59 (Protectin).
    纯化方法
    Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.
    纯度
    > 95 % (by SDS-PAGE).
    免疫原
    Human peripheral blood lymphocytes
    克隆位点
    MEM-129
    亚型
    IgM
    Top Product
    Discover our top product CD59 Primary Antibody
  • 应用备注
    Flow Cytometry. Functional Studies (The antibody activates T-cells).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD59
    别名
    CD59 (CD59 产品)
    别名
    16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
    背景
    CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
    基因ID
    966
    UniProt
    P13987
    途径
    Complement System
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