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GDNF 抗体 (Biotin)

GDNF 适用: 人 WB, IHC (fro), EIA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN116020
发货至: 中国
  • 抗原 See all GDNF 抗体
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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    宿主
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    克隆类型
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    多克隆
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    This GDNF antibody is conjugated to Biotin
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    Human Glial Derived Neurotrophic Factor.
    纯化方法
    Affinity chromatography.
    免疫原
    Highly pure (>98%) recombinant hGDNF.
    Top Product
    Discover our top product GDNF Primary Antibody
  • 应用备注
    ELISA: To detect hGDNF by direct ELISA (using 100 ml/well antibody solution) this GDNFantibody can be used at a concentration of 0.15-0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinanthGDNF. Western Blot: To detect hGDNF by Western Blot analysis this GDNF antibody can be used ata concentration of 0.1-0.2 mg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hGDNF is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS, pH 7.2 without preservatives.
    储存液
    Without preservative
    注意事项
    Centrifuge vial prior to opening! This product is photosensitive and should be protected from light
    储存条件
    4 °C
    储存方法
    Store the antibody at 2-8 °C. DO NOT FREEZE!
  • 抗原
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    别名
    GDNF (GDNF 产品)
    别名
    gdnf antibody, GDNF antibody, AI385739 antibody, gdnfa antibody, hfb1-gdnf antibody, ATF1 antibody, ATF2 antibody, HFB1-GDNF antibody, HSCR3 antibody, glial cell derived neurotrophic factor antibody, glial cell derived neurotrophic factor a antibody, glial cell line derived neurotrophic factor antibody, glial cell derived neurotrophic factor L homeolog antibody, Gdnf antibody, gdnfa antibody, GDNF antibody, gdnf.L antibody
    背景
    Glial cell line derived neurotrophic factor (GDNF) is a highly conserved neurotrophic factor that is a distant member of the TGF beta superfamily. The GDNF gene product is processed to a disulphide-linked homodimer, which is a ligand for the RET protooncogene. GDNF protects and repairs dopamine-containing neurons, which degenerate in Parkinson's disease, and motor neurons, which die in amyotrophic lateral sclerosis. The use of GDNF in the treatment of Parkinson's disease has shown promise in the clinic. Treatment of spinal cord injuries with GDNF has also produced neurological improvement.Synonyms: ATF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor
    基因ID
    2668
    NCBI登录号
    NP_000505
    UniProt
    P39905
    途径
    RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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