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GDNF 抗体 (AA 109-211)

GDNF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7267388
发货至: 中国
  • 抗原 See all GDNF 抗体
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    抗原表位
    • 16
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 109-211
    适用
    • 78
    • 43
    • 32
    • 16
    • 16
    • 1
    宿主
    • 73
    • 6
    • 4
    • 3
    克隆类型
    • 72
    • 13
    • 1
    多克隆
    标记
    • 39
    • 10
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GDNF antibody is un-conjugated
    应用范围
    • 76
    • 31
    • 26
    • 19
    • 17
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    原理
    GDNF Rabbit pAb
    序列
    RGQRGKNRGC VLTAIHLNVT DLGLGYETKE ELIFRYCSGS CDAAETTYDK ILKNLSRNRR LVSDKVGQAC CRPIAFDDDL SFLDDNLVYH ILRKHSAKRC GCI
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 109-211 of human GDNF (NP_000505.1).
    亚型
    IgG
    Top Product
    Discover our top product GDNF Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    别名
    GDNF (GDNF 产品)
    别名
    gdnf antibody, GDNF antibody, AI385739 antibody, gdnfa antibody, hfb1-gdnf antibody, ATF1 antibody, ATF2 antibody, HFB1-GDNF antibody, HSCR3 antibody, glial cell derived neurotrophic factor antibody, glial cell derived neurotrophic factor a antibody, glial cell line derived neurotrophic factor antibody, glial cell derived neurotrophic factor L homeolog antibody, Gdnf antibody, gdnfa antibody, GDNF antibody, gdnf.L antibody
    背景
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing.,GDNF,ATF,ATF1,ATF2,HFB1-GDNF,HSCR3,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Other Neurological disorders,Amyotrophic lateral sclerosis-ALS,GDNF
    分子量
    18kDa/20kDa/22kDa/23kDa/25kDa
    基因ID
    2668
    UniProt
    P39905
    途径
    RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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