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IL1A 抗体

IL1A 适用: 小鼠 WB, EIA, Func 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN115862
发货至: 中国
  • 抗原 See all IL1A 抗体
    IL1A (Interleukin 1 alpha (IL1A))
    适用
    • 107
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    小鼠
    宿主
    • 143
    • 36
    • 10
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    克隆类型
    • 158
    • 40
    多克隆
    标记
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    This IL1A antibody is un-conjugated
    应用范围
    • 145
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    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody recats with Murine-1 alpha.
    纯化方法
    Affinity chromatography
    免疫原
    Highly pure (>98%) recombinant mIL-1-alpha (murine IL-1 alpha).
    Top Product
    Discover our top product IL1A Primary Antibody
  • 应用备注
    Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of mIL-1 alpha (0.05 ng/mL), a concentration of 0.03-0.05 μg/mL of this antibody is required. ELISA: (Indirect): To detect mIL-1 alpha by indirect ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant mIL-1 alpha. (Sandwich): To detect mIL-1 alpha by sandwich ELISA (using 100 μL/well antibody solution)a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with Biotinylated Anti-Murine IL-1 alpha (PP005B) as a detectionantibody, allows the detection of at least 0.2-0.4 ng/well of recombinant mIL-1 alpha. Western blot: To detect mIL-1 alpha by Western blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS, pH 7.2 without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    IL1A (Interleukin 1 alpha (IL1A))
    别名
    Interleukin-1 alpha / IL-1A (IL1A 产品)
    别名
    IL-1A antibody, IL1 antibody, IL1-ALPHA antibody, IL1F1 antibody, IL-6 antibody, Il-1a antibody, IL-1 alpha antibody, IL-1alpha antibody, L1A antibody, interleukin 1 alpha antibody, interleukin 6 antibody, IL1A antibody, IL6 antibody, Il1a antibody
    背景
    Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin 1 alpha (IL1 alpha) and interleukin 1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25 % homology in their amino acid sequence.Synonyms: Hematopoietin-1, IL-1 alpha, IL1A, IL1F1
    基因ID
    16175
    NCBI登录号
    NP_034684
    UniProt
    P01582
    途径
    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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