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FAS 抗体 (N-Term)

Name: FAS 抗体 (N-Term)
SKU: ABIN1106611
Availability: OutOfStock

FAS 适用: 大鼠, 小鼠 WB, IF, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated

Lane 1: Recombinant Mouse FAS Protein 10ng. (FAS 抗体 (N-Term))

Immunocytochemical staining of HeLa Cells (FAS 抗体 (N-Term))

Paraffin Rat Spleen tissue lysate stained with CD95 / FAS (FAS 抗体 (N-Term))

IHC (p)

3 images

产品编号 ABIN1106611

发货至: 中国

Datasheet as PDF

抗原 See all FAS 抗体

FAS (TNF Receptor Superfamily, Member 6 (FAS))
抗原表位
25

16

16

8

8

6

5

5

4

4

4

4

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
210

67

62

19

6

4

2

2

1

1
大鼠, 小鼠
宿主
158

86

4

2

1

1

1

1
兔
Compatible Secondaries
克隆类型
156

96

1
多克隆
标记
120

27

25

12

10

7

4

4

3

3

3

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This FAS antibody is un-conjugated
应用范围
163

115

72

64

35

34

30

26

26

20

18

9

8

6

5

4

4

2

2

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

特异性

Recognizes FAS. No cross reactivity with other proteins.

纯化方法

Immunoaffinity Chromatography

免疫原

A synthetic peptide corresponding to a sequence at the N-terminal of Rat FAS, different from the related Mouse sequence by seven amino acids.

亚型

IgG

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anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 21-170) antibody
FAS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 26-96) antibody
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anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibody
FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 5B4 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibody
FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibody
FAS 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
溶解方式

Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.

浓度

0.5 mg/mL

缓冲液

0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide, 5 mg BSA

储存液

Sodium azide, Thimerosal (Merthiolate)

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

FAS (TNF Receptor Superfamily, Member 6 (FAS))

别名

CD95 / FAS (FAS 产品)

别名

ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody

背景

FAS (also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors, can induce apoptosis or, conversely, can deliver growth stimulatory signals. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor (TNF) receptors and the low-affinity nerve growth factor receptor (NGFR) and is mapped to 10q24.1. And the FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis.Synonyms: APT1, Apo-1 antigen, FAS1, FASLG receptor, TNFRSF6, Tumor necrosis factor receptor superfamily member 6

基因ID

14102

NCBI登录号

NP_032013

UniProt

P25446

途径

p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity