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Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways (By similarity).. 再加上，我们可以发CDKN2A Interacting Protein 蛋白 (7) 和 CDKN2A Interacting Protein 试剂盒 (3)和数多这个蛋白质的别的产品。
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Oncogenic functions of CARF in hepatocellular carcinoma tumorigenesis is a result of activation of beta-catenin (显示 CTNNB1 抗体)/TCF (显示 HNF4A 抗体) signaling.
CARF promotes carcinogenesis in p53 (显示 TP53 抗体)-deficient cells by repressing p21WAF1 and promoting cell cycle progression.
The results suggest that CARF regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 (显示 XRN2 抗体) between the nucleoplasm and nucleolus.
CARF regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling.
Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66 (显示 WDR66 抗体), USP20 (显示 USP20 抗体) and OR7C2 (显示 OR7C2 抗体) in a Korean population.
CARF knockdown elicited DNA damage response as evidenced by increased levels of phosphorylated ATM (显示 ATM 抗体) and gammaH2AX (显示 H2AFX 抗体), leading to induction of mitotic arrest and eventual apoptosis.
CARF may act as a novel key regulator of the p53 (显示 TP53 抗体) pathway at multiple checkpoints
cooperates with human p14ARF in activating p53 (显示 TP53 抗体)
CARF may exert a vital control on p53 (显示 TP53 抗体)-HDM2-p21(WAF1 (显示 CDKN1A 抗体)) pathway that is central to the cell cycle control, senescence, and DNA damage response of human cells
CARF exerts a vital control on the p53 (显示 TP53 抗体)-HDM2-p21WAF1 pathway that is frequently altered in cancer cells.
Activates p53/TP53 by CDKN2A-dependent and CDKN2A- independent pathways (By similarity).
, collaborates/cooperates with ARF (alternate reading frame) protein
, collaborator of ARF
, CDKN2A interacting protein
, protein CDKN2AIP homolog A