anti-WWTR1 (WWTR1) 抗体产品概述

Full name:
anti-WW Domain Containing Transcription Regulator 1 抗体 (WWTR1)
在www.antibodies-online.cn可供53 WW Domain Containing Transcription Regulator 1 (WWTR1) 抗体的13不同的供货商。 再加上,我们可以发WWTR1 蛋白 (5)WWTR1 试剂盒 (2)和数多这个蛋白质的别的产品。 总共64 WWTR1产品已列进来了。
别名:
2310058J06Rik, 2610021I22Rik, C78399, Taz, WWTR1
列出全部抗体 基因 基因ID UniProt
WWTR1 25937 Q9GZV5
WWTR1 97064 Q9EPK5
WWTR1 295062  

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引用最多的anti-WWTR1 抗体

  1. Human Polyclonal WWTR1 Primary Antibody for WB - ABIN153163 : Chan, Lim, Guo, Ng, Lee, Hunziker, Zeng, Hong: A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. in Cancer research 2008 (PubMed)
    Show all 8 references for 153163

  2. Human Polyclonal WWTR1 Primary Antibody for ChIP, ICC - ABIN258561 : Strakova, Reed, Ihnatovych: Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization. in Biology of reproduction 2010 (PubMed)
    Show all 6 references for 258561

  3. Human Polyclonal WWTR1 Primary Antibody for EIA, WB - ABIN955592 : Remue, Meerschaert, Oka, Boucherie, Vandekerckhove, Sudol, Gettemans: TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner. in FEBS letters 2010 (PubMed)
    Show all 5 references for 955592

  4. Human Polyclonal WWTR1 Primary Antibody for ICC, IF - ABIN4357944 : Bhat, Salazar, Balasubramaniyan, Wani, Heathcock, Hollingsworth, James, Gumin, Diefes, Kim, Turski, Azodi, Yang, Doucette, Colman, Sulman, Lang, Rao, Copray, Vaillant, Aldape: The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. in Genes & development 2011 (PubMed)
    Show all 3 references for 4357944

  5. Cow (Bovine) Polyclonal WWTR1 Primary Antibody for WB - ABIN2779708 : Hong, Hwang, McManus, Amsterdam, Tian, Kalmukova, Mueller, Benjamin, Spiegelman, Sharp, Hopkins, Yaffe: TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. in Science (New York, N.Y.) 2005 (PubMed)

更多抗WWTR1的相互作用对抗体

Zebrafish WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Yap (显示 YAP1 抗体)/Taz (显示 TAZ 抗体)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  2. Taz (显示 TAZ 抗体) is required in the anteroposterior patterning of the pronephric progenitor domain in the intermediate mesoderm, acting in part by regulating retinoic acid signaling in the pronephric progenitor field in the intermediate mesoderm.

  3. Taz (显示 TAZ 抗体)-depleted larvae displayed patterning defects in ventral cranial vessels that correlate with lateral displacement of thyroid follicles

  4. When transcriptional coactivators Yap (显示 YAP1 抗体) and Taz (显示 TAZ 抗体) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  5. TAZ (显示 TAZ 抗体) has a critical role in osteoblast differentiation in vivo

Human WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. results provide evidence that TAZ (显示 TAZ 抗体) and miR (显示 MLXIP 抗体)-135b engage in a positive feedback loop to regulate epithelial-mesenchymal transition and metastasis in osteosarcoma, and suggest that both factors can be therapeutic targets for osteosarcoma treatment.

  2. extracellular matrix stiffening sustains vascular cell growth and migration through YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体)-dependent glutaminolysis and anaplerosis

  3. a stiffness-dependent YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体)-mediated positive feedback loop that drives remodeling phenotypes in pulmonary artery smooth muscle cells via reduced COX-2 (显示 COX2 抗体) and prostaglandin activity.

  4. ETAR (显示 EDNRA 抗体) stimulation acted via downstream G-protein Galphaq (显示 GNAQ 抗体)/11 and Rho GTPase (显示 RACGAP1 抗体) to suppress the Hippo pathway, thus leading to YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) activation, which was required for ETAR (显示 EDNRA 抗体)-induced tumorigenesis. Overall, these results indicate a critical role of the YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) axis in ETAR (显示 EDNRA 抗体) signaling

  5. Various studies show that in human cancers, the Hippo pathway is frequently deregulated allowing YAP1 (显示 YAP1 抗体) and TAZ (显示 TAZ 抗体) to escape the inhibition by the Hippo pathway. The upregulation of YAP1 (显示 YAP1 抗体) and TAZ (显示 TAZ 抗体) induces epithelial-mesenchymal transition and increases drug resistance in cancer cells. TAZ (显示 TAZ 抗体) is implicated in cancer stemness.[review]

  6. Results demonstrate a pivotal role for TAZ (显示 TAZ 抗体) in regulating the differentiation of Treg cells and TH17 cells.

  7. the transcription regulators YAP (显示 YAP1 抗体) and TAZ (显示 TAZ 抗体) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  8. In colorectal carcinoma TIAM1 (显示 TIAM1 抗体) suppresses tumor progression by regulating YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) activity.

  9. Growing evidence suggests that transcriptional effectors of the Hippo pathway, YAP (显示 YAP1 抗体) and TAZ (显示 TAZ 抗体), promote resistance to various anti-cancer therapies, including cytotoxic chemotherapy, molecular targeted therapy, and radiation therapy. [review]

  10. SGK1 (显示 SGK1 抗体) promotes YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) transcriptional activity. SGK1 (显示 SGK1 抗体) enhances YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) activity by upregulating YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体). SGK1 (显示 SGK1 抗体) is a transcriptional target of YAP (显示 YAP1 抗体). SGK1 (显示 SGK1 抗体) stabilizes TAZ (显示 TAZ 抗体) by inhibiting GSK3beta (显示 GSK3b 抗体).

Mouse (Murine) WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Yap (显示 YAP1 抗体) and Taz (显示 TAZ 抗体) leads to impaired epicardial epithelial-to-mesenchymal transition (EMT (显示 ITK 抗体)) and a reduction in epicardial cell proliferation and differentiation into coronary endothelial cells.

  2. This study identifies YAP/TAZ as central mediators of VEGF signaling

  3. TAZ (显示 TAZ 抗体) is required for TGFbeta (显示 TGFB1 抗体) induction of smooth muscle genes and is also required for the differentiated VSMC phenotype; synergy between TAZ (显示 TAZ 抗体) and SRF, and TAZ (显示 TAZ 抗体) and Myocardin (显示 MYOCD 抗体) (MyoC856), in regulating smooth muscle gene activation was observed in primary aortic vascular smooth muscle cells.

  4. Results demonstrate a pivotal role for TAZ (显示 TAZ 抗体) in regulating the differentiation of Treg cells and TH17 cells.

  5. ABL (显示 ABL1 抗体) potentiated the assembly and activation of the RUNX2 (显示 RUNX2 抗体)-TAZ (显示 TAZ 抗体) master transcription factor complex that is required for osteoblastogenesis, while antagonizing PPARgamma (显示 PPARG 抗体)-mediated adipogenesis.

  6. the transcription regulators YAP (显示 YAP1 抗体) and TAZ (显示 TAZ 抗体) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  7. These results suggest that vinculin (显示 VCL 抗体) promotes the nuclear localization of transcription factor TAZ (显示 TAZ 抗体) to inhibit the adipocyte differentiation on rigid extracellular matrix.

  8. TAZ (显示 TAZ 抗体) represents a previously unrecognized factor that contributes to the critical process of steatosis-to-Nonalcoholic Steatohepatitis progression.

  9. both Snail (显示 SNAI1 抗体) and Slug (显示 SNAI2 抗体) are able to form binary complexes with either YAP (显示 YAP1 抗体) or TAZ (显示 TAZ 抗体) that, together, control YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) transcriptional activity and function throughout mouse development.

  10. results demonstrate that skeletal stem/stromal cell mobilize Snail (显示 SNAI1 抗体)/Slug (显示 SNAI2 抗体)-YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) complexes to control stem cell function

WWTR1 抗原简介

Antigen Summary

This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with WWTR1

  • WW domain containing transcription regulator 1 (wwtr1) 抗体
  • WW domain containing transcription regulator 1 (WWTR1) 抗体
  • WW domain containing transcription regulator 1 (Wwtr1) 抗体
  • 2310058J06Rik 抗体
  • 2610021I22Rik 抗体
  • C78399 抗体
  • Taz 抗体
  • WWTR1 抗体

Protein level used designations for WWTR1

WW domain containing transcription regulator 1 , WW domain-containing transcription regulator protein 1 , taz , WW domain-containing transcription regulator protein 1-like , transcriptional co-activator with PDZ-binding motif , transcriptional coactivator with PDZ-binding motif , transcriptional coactivator with PDZ binding motif , transcriptional co-activator with PDZ-binding motif (TA)Z , transcriptional co-activator with PDZ-binding motif (TAZ)

GENE ID SPECIES
496155 Xenopus laevis
568008 Danio rerio
100050661 Equus caballus
100401831 Callithrix jacchus
100437619 Pongo abelii
100493170 Xenopus (Silurana) tropicalis
100522573 Sus scrofa
100592028 Nomascus leucogenys
25937 Homo sapiens
609743 Canis lupus familiaris
614786 Bos taurus
97064 Mus musculus
295062 Rattus norvegicus
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