anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) 抗体产品概述

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anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 抗体 (KLRK1)
在www.antibodies-online.cn可供206 Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) 抗体的24不同的供货商。 再加上,我们可以发Killer Cell Lectin-Like Receptor Subfamily K, Member 1 蛋白 (21)Killer Cell Lectin-Like Receptor Subfamily K, Member 1 试剂盒 (3)和数多这个蛋白质的别的产品。 总共238 Killer Cell Lectin-Like Receptor Subfamily K, Member 1产品已列进来了。
别名:
CD314, D6H12S2489E, D12S2489E, KLR, KLRK1, NKG2-D, Nkg2d, Nkrp2

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  1. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN4898794 : Lee, Kang, Yoon, Jin, Song, Her, Kang, Hwang, Kang, Joo, Nam: Natural killer (NK) cells inhibit systemic metastasis of glioblastoma cells and have therapeutic effects against glioblastomas in the brain. in BMC cancer 2015 (PubMed)
    Show all 19 references for 4898794

  2. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN320264 : Das, Sugita, Brenner: Mechanisms of Vdelta1 gammadelta T cell activation by microbial components. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
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  3. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN120295 : Bauer, Groh, Wu, Steinle, Phillips, Lanier, Spies: Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 6 references for 120295

  4. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN4898788 : Vossen, Matmati, Hertoghs, Baars, Gent, Leclercq, Hamann, Kuijpers, van Lier: CD27 defines phenotypically and functionally different human NK cell subsets. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
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  5. Human Monoclonal KLRK1 Primary Antibody for FACS, IHC (fro) - ABIN120294 : Groh, Bruhl, El-Gabalawy, Nelson, Spies: Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
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  6. Human Polyclonal KLRK1 Primary Antibody for IF (p), IHC (p) - ABIN730078 : Mozer-Lisewska, Mania, Kowala-Piaskowska, Kluk, Samara, Pauli, ?eromski: Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers. in Archivum immunologiae et therapiae experimentalis 2014 (PubMed)
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  7. Human Monoclonal KLRK1 Primary Antibody for FACS, Func - ABIN260439 : Vitales-Noyola, Martínez-Martínez, Loyola-Rodríguez, Baranda, Niño-Moreno, González-Amaro: Quantitative and functional analysis of CD69(+) T regulatory lymphocytes in patients with periodontal disease. in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016 (PubMed)
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  8. Human Monoclonal KLRK1 Primary Antibody for FACS - ABIN4898792 : van Meijgaarden, Haks, Caccamo, Dieli, Ottenhoff, Joosten et al.: Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human ... in PLoS pathogens 2015 (PubMed)
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  9. Human Polyclonal KLRK1 Primary Antibody for ELISA, WB - ABIN185435 : Hayakawa, Smyth: Innate immune recognition and suppression of tumors. in Advances in cancer research 2006 (PubMed)
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更多抗Killer Cell Lectin-Like Receptor Subfamily K, Member 1的相互作用对抗体

Human Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. Supporting a role for NKG2D ligand expression in controlling the progression of early-stage B cell lymphomas in humans, we found higher expression of a microRNA that inhibits human NKG2D ligand expression in tumor cells from high-grade compared with low-grade follicular lymphoma patients.

  2. On-treatment decrease of NKG2D correlates to early emergence of clinically evident hepatocellular carcinoma after interferon (显示 IFNA 抗体)-free therapy for chronic hepatitis C

  3. The interaction of Fas receptor (显示 FAS 抗体) with FasL (显示 FASL 抗体) leads to an activation of the Tag7 (显示 PGLYRP1 抗体)-Hsp70 (显示 HSP70 抗体) complex in the lymphocyte membrane fraction, and here FasL (显示 FASL 抗体) acts as a receptor that induces intracellular signaling in lymphocytes.An interaction of the MicA (显示 MICA 抗体) stress ligand with the NKG2D receptor is necessary for the release of this cytotoxic complex

  4. Blockade of NKG2D on CD8 (显示 CD8A 抗体)(+) T cells inhibited the migration over ligand-expressing endothelial cells. Intestinal induction of NKG2D ligands and ligand-induced down-regulation of NKG2D in Crohn's disease (CD) suggest that the NKG2D-ligand interaction may be involved in both the activation and recruitment of NKG2D(+) lymphocytes into the inflamed CD intestine.

  5. IDH (显示 IDH1 抗体) mutant glioma cells acquire resistance to natural killer cells through epigenetic silencing of NKG2D ligands ULBP1 (显示 ULBP1 抗体) and ULBP3 (显示 ULBP3 抗体)

  6. non-virally infected human T cells can express NKG2DL, with implications for stress surveillance by the large number of NKG2D-expressing NK cells sequestered in the liver.

  7. After PSK (显示 TAOK2 抗体) administration, INF (显示 GIF 抗体)-g production in CD8 (显示 CD8A 抗体)(+) T cells increased in mice with cells expressing neither Rae-1 (显示 RAE1 抗体) nor H60, but did not change in mice implanted with cells expressing both Rae-1 (显示 RAE1 抗体) and H60. We demonstrated that the expression of NKG2DLs affects tumor immunity and the efficacy of immuno therapy in tumor-bearing mouse model

  8. These results suggest the involvement of HIV-1 nef and human NKG2D-NKG2D ligand interactions in the enhanced susceptibility of HIV-1-infected cells from HIV elite controllers to antibody-dependent cellular cytotoxicity responses.

  9. Blocking the interaction of NKG2D with its ligands deleted the sensitizing effects of HCQ. In addition, we showed that HCQ did not affect the synthesis or degradation of ULBP4 (显示 RAET1E 抗体), but induced the translocation of ULBP4 (显示 RAET1E 抗体) from the cytoplasm to the cell membrane

  10. High NKG2D expression is associated with hepatocellular carcinoma.

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. proposed that TLR9 (显示 TLR9 抗体) regulates the NF-kappaB (显示 NFKB1 抗体)-NLRP3 (显示 NLRP3 抗体)-IL-1beta (显示 IL1B 抗体) pathway negatively in Salmonella-induced NKG2D-mediated intestinal inflammation and plays a critical role in defense against S. typhimurium infection and in the protection of intestinal integrity.

  2. NKG2D-deficient mice and mice constitutively expressing NKG2D ligands had increased incidence of B cell tumors, confirming that the inability to clear NKG2D ligand-expressing cells was important in tumor suppression and that NKG2D ligand expression is a marker of nascent tumors

  3. data show that NKG2D has a nonredundant role in priming of CD8 (显示 CD8A 抗体)(+) T cells to produce antiviral cytokines

  4. NKG2D augments Ly49H (显示 KLRA8 抗体)-dependent proliferation of NK cells; however, NKG2D signaling alone is inadequate for expansion of NK cells, likely due to only transient expression of the NKG2D-DAP12 (显示 TYROBP 抗体) complex

  5. The elevated cytotoxicity achieved by suppressing mTOR (显示 FRAP1 抗体) was a result of up-regulation of NKG2D and TNF-alpha (显示 TNF 抗体). The inhibition of STAT5 (显示 STAT5A 抗体) pathways via siRNA interference or a specific inhibitor eliminated the up-regulation of NKG2D and TNF-alpha (显示 TNF 抗体) in rapamycin-treated Vgamma4 gammadelta T cells.

  6. study demonstrates that the effect of NKG2D on B1a cell development occurs at a developmental stage that precedes the common lymphoid progenitor; findings reveal an unexpected new role for NKG2D in the regulation of B1a cell development

  7. Sirt6 (显示 SIRT6 抗体) binds to promoters of NKG2D ligand genes and regulates the H3K9 and H3K56 acetylation levels

  8. These results support the conclusion that svH1C mimics Neu5Ac-containing sequences and interacts with cell-surface receptor NKG2D, which contains a lectin-like domain

  9. These results indicate that, unlike in the pancreas, NKG2D-NKG2D ligand interaction does not play a critical role in obesity-induced inflammation in the adipose tissue.

  10. The results show that NK cells and the NKG2D receptor play a role in control of lymphomas, and that selection of NKG2D-ligand (MULT1 (显示 ULBP1 抗体)) loss mutants provides a mechanism for tumor escape.

Pig (Porcine) Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. The effect of Bacillus cereus on the stress response of enterocytes, including the expression of NKG2D, is reported.

Rhesus Monkey Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) interaction partners

  1. Determined expressions of NKG2D in decidual natural killer cells in patients having spontaneous abortions.

Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) 抗原简介

Antigen Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.

Alternative names and synonyms associated with Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)

  • killer cell lectin-like receptor subfamily K, member 1 (KLRK1) 抗体
  • NKG2-D type II integral membrane protein-like (LOC100398970) 抗体
  • killer cell lectin-like receptor subfamily K, member 1 (Klrk1) 抗体
  • NKG2D protein (NKG2D) 抗体
  • CD314 抗体
  • D6H12S2489E 抗体
  • D12S2489E 抗体
  • KLR 抗体
  • KLRK1 抗体
  • NKG2-D 抗体
  • Nkg2d 抗体
  • Nkrp2 抗体

Protein level used designations for KLRK1

killer cell lectin-like receptor subfamily K, member 1 , NKG2-D type II integral membrane protein-like , NK cell receptor D , NKG2-D type II integral membrane protein , NKG2-D-activating NK receptor , natural killer cell group 2D , NK lectin-like receptor , NKLLR , NKR-P2, ortholog of human NKG2D , killer cell lectin-like receptor subfamily K member 1 , NKG2-D activating NK receptor

GENE ID SPECIES
611355 Canis lupus familiaris
100126736 Papio anubis
100398970 Callithrix jacchus
22914 Homo sapiens
27007 Mus musculus
24934 Rattus norvegicus
396737 Sus scrofa
450153 Pan troglodytes
574240 Macaca mulatta
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