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KPNB1 抗体

(Karyopherin (Importin) beta 1 (KPNB1))
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013].
KPNB1 抗体  (C-Term) KPNB1 抗体  (C-Term) KPNB1 抗体 (C-Term) (ABIN185516)

Verified KPNB1 适用: 人, 大鼠 WB, ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated

KPNB1 抗体  (AA 250-350) KPNB1 抗体  (AA 250-350) KPNB1 抗体 (AA 250-350) (ABIN6142997)

KPNB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

KPNB1 抗体 KPNB1 抗体 KPNB1 抗体 (ABIN7074398)

KPNB1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

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Find KPNB1 抗体 for a variety of species such as anti-Human KPNB1, anti-Mouse KPNB1, anti-Rat KPNB1. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular KPNB1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC, FACS, IF
Validations
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Cat. No. ABIN185516
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6142997
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (2)
Cat. No. ABIN7074398
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7156134
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7239089
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN390792
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS
Validations
  • (3)
Cat. No. ABIN3002817
Quantity 400 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6747483
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p), FACS
Validations
  • (1)
Cat. No. ABIN2611830
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN5013820
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2788708
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN702775
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN702777
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5007907
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5007908
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our KPNB1 抗体

Li, Zhao, Xu, Zhang, Zhang, Xiao, Gao, Tian, Zeng, Lee, Tarakanova, Lan, Feng, Feng: "Antiviral activity of a purine synthesis enzyme reveals a key role of deamidation in regulating protein nuclear import." in: Science advances, Vol. 5, Issue 10, pp. eaaw7373, (2019) (PubMed).

Di Benedetto, Sun, Zambonin, Tamma, Nico, Calvano, Colaianni, Ji, Mori, Grano, Lu, Colucci, Yuen, New, Zallone, Zaidi: "Osteoblast regulation via ligand-activated nuclear trafficking of the oxytocin receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 46, pp. 16502-7, (2014) (PubMed).

Arnold, Nath, Hauber, Kehlenbach: "Multiple importins function as nuclear transport receptors for the Rev protein of human immunodeficiency virus type 1." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20883-90, (2006) (PubMed).

Caudron, Bunt, Bastiaens, Karsenti: "Spatial coordination of spindle assembly by chromosome-mediated signaling gradients." in: Science (New York, N.Y.), Vol. 309, Issue 5739, pp. 1373-6, (2005) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Wamhoff, Bowles, Dietz, Hu, Sturek: "Exercise training attenuates coronary smooth muscle phenotypic modulation and nuclear Ca2+ signaling." in: American journal of physiology. Heart and circulatory physiology, Vol. 283, Issue 6, pp. H2397-410, (2002) (PubMed).

Wiese, Wilde, Moore, Adam, Merdes, Zheng: "Role of importin-beta in coupling Ran to downstream targets in microtubule assembly." in: Science (New York, N.Y.), Vol. 291, Issue 5504, pp. 653-6, (2001) (PubMed).

Iborra, Jackson, Cook: "The path of RNA through nuclear pores: apparent entry from the sides into specialized pores." in: Journal of cell science, Vol. 113 Pt 2, pp. 291-302, (2000) (PubMed).

Rexach, Blobel: "Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins." in: Cell, Vol. 83, Issue 5, pp. 683-92, (1996) (PubMed).

Radu, Blobel, Moore: "Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1769-73, (1995) (PubMed).

Aliases for KPNB1 抗体

importin beta-1 subunit (AFUA_1G15720) 抗体
importin beta-1 subunit (AOR_1_1974174) 抗体
Importin beta-1 subunit (Bm1_57540) 抗体
importin beta-1 subunit (PMAA_065830) 抗体
importin beta-1 subunit (AFLA_083750) 抗体
importin beta-1 subunit (TSTA_085870) 抗体
importin beta-1 subunit (BDBG_07509) 抗体
importin beta-1 subunit (MCYG_00039) 抗体
karyopherin (importin) beta 1 L homeolog (kpnb1.L) 抗体
importin beta 1 (LOC100533387) 抗体
karyopherin subunit beta 1 (KPNB1) 抗体
karyopherin (importin) beta 1 (Kpnb1) 抗体
karyopherin subunit beta 1 (Kpnb1) 抗体
AA409963 抗体
Afu1g15720 抗体
AO090005001133 抗体
imb1 抗体
IMB1 抗体
impnb 抗体
Impnb 抗体
ipo1 抗体
IPO1 抗体
ipob 抗体
IPOB 抗体
ntf97 抗体
NTF97 抗体
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