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KLRK1 抗体 (Internal Region)

KLRK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855938
发货至: 中国
  • 抗原 See all KLRK1 抗体
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    抗原表位
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    Internal Region
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This KLRK1 antibody is un-conjugated
    应用范围
    • 45
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    产品特性
    Rabbit Polyclonal antibody to NKG2D (killer cell lectin-like receptor subfamily K, member 1)
    NKG2D antibody [N3C2], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human NKG2D. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product KLRK1 Primary Antibody
  • 应用备注
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: human spleen

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.82 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    别名
    NKG2D (KLRK1 产品)
    别名
    KLRK1 antibody, NKG2D antibody, CD314 antibody, D12S2489E antibody, KLR antibody, NKG2-D antibody, D6H12S2489E antibody, Nkg2d antibody, Nkrp2 antibody, killer cell lectin like receptor K1 antibody, killer cell lectin-like receptor subfamily K, member 1 antibody, NKG2D protein antibody, KLRK1 antibody, Klrk1 antibody, NKG2D antibody
    背景
    Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.

    Cellular Localization: Membrane, Single-pass type II membrane protein
    分子量
    25 kDa
    基因ID
    22914
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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