电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

KLRK1 抗体 (AA 73-216)

KLRK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7161645
发货至: 中国
  • 抗原 See all KLRK1 抗体
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    抗原表位
    • 16
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 73-216
    适用
    • 54
    • 32
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 17
    • 3
    • 2
    • 2
    • 1
    克隆类型
    • 53
    • 24
    • 2
    多克隆
    标记
    • 34
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLRK1 antibody is un-conjugated
    应用范围
    • 45
    • 42
    • 14
    • 14
    • 14
    • 13
    • 11
    • 10
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human NKG2-D type II integral membrane protein (73-216AA)
    亚型
    IgG
    Top Product
    Discover our top product KLRK1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    别名
    KLRK1 (KLRK1 产品)
    别名
    KLRK1 antibody, NKG2D antibody, CD314 antibody, D12S2489E antibody, KLR antibody, NKG2-D antibody, D6H12S2489E antibody, Nkg2d antibody, Nkrp2 antibody, killer cell lectin like receptor K1 antibody, killer cell lectin-like receptor subfamily K, member 1 antibody, NKG2D protein antibody, KLRK1 antibody, Klrk1 antibody, NKG2D antibody
    背景

    Background: Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4.

    Aliases: CD314 antibody, CD314 antigen antibody, D12S2489E antibody, Killer cell lectin like receptor subfamily K member 1 antibody, Killer cell lectin-like receptor subfamily K member 1 antibody, KLR antibody, KLRC4 KLRK1 readthrough antibody, KLRK1 antibody, NK cell receptor D antibody, NK lectin-like receptor antibody, NKG2 D activating NK receptor antibody, NKG2 D type II integral membrane protein antibody, NKG2-D antibody, NKG2-D type II integral membrane protein antibody, NKG2-D-activating NK receptor antibody, Nkg2d antibody, NKG2D_HUMAN antibody, NKLLR antibody, NKR P2 antibody, Nkrp2 antibody

    UniProt
    P26718
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
You are here: