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Ubiquilin 2 抗体

(Ubiquilin 2 (UBQLN2))
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases\; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein. [provided by RefSeq, Oct 2009].
Ubiquilin 2 抗体  (AA 555-624) Ubiquilin 2 抗体  (AA 555-624) Ubiquilin 2 抗体 (AA 555-624) (ABIN565449)

UBQLN2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5F5 unconjugated

Ubiquilin 2 抗体  (AA 1-150) Ubiquilin 2 抗体  (AA 1-150) Ubiquilin 2 抗体 (AA 1-150) (ABIN6149859)

UBQLN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Ubiquilin 2 抗体  (N-Term) Ubiquilin 2 抗体  (N-Term) Ubiquilin 2 抗体 (N-Term) (ABIN542720)

UBQLN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Ubiquilin 2 抗体 by 适用

Find Ubiquilin 2 抗体 for a variety of species such as anti-Human Ubiquilin 2, anti-Mouse Ubiquilin 2, anti-Rat Ubiquilin 2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Ubiquilin 2 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find Ubiquilin 2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

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Find Ubiquilin 2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Ubiquilin 2 抗体 by 克隆形成能力

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Ubiquilin 2 抗体 by 克隆

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Ubiquilin 2 抗体 by 标记

Find Ubiquilin 2 抗体 with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Ubiquilin 2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (11)
  • (7)
Cat. No. ABIN565449
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6149859
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (3)
Cat. No. ABIN542720
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7174228
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7264828
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN7436396
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN526207
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7248278
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
  • (1)
Cat. No. ABIN542719
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6265861
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Monkey, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6745296
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN1580461
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2774254
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN357609
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7174231
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Ubiquilin 2 抗体

Alexander, Ghanbari Niaki, Zhang, Sarkar, Liu, Nirujogi, Pandey, Myong, Wang: "Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 49, pp. E11485-E11494, (2019) (PubMed).

Sharkey, Safren, Pithadia, Gerson, Dulchavsky, Fischer, Patel, Lantis, Ashraf, Kim, Meliki, Minakawa, Barmada, Ivanova, Paulson: "Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 44, pp. E10495-E10504, (2018) (PubMed).

Yau, Doerner, Castellanos, Haakonsen, Werner, Wang, Yang, Martinez-Martin, Matsumoto, Dixit, Rape: "Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control." in: Cell, Vol. 171, Issue 4, pp. 918-933.e20, (2017) (PubMed).

Hjerpe, Bett, Keuss, Solovyova, McWilliams, Johnson, Sahu, Varghese, Wood, Wightman, Osborne, Bates, Glickman, Trost, Knebel, Marchesi, Kurz: "UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome." in: Cell, Vol. 166, Issue 4, pp. 935-49, (2016) (PubMed).

Le, Chang, Kovlyagina, Georgiou, Safren, Braunstein, Kvarta, Van Dyke, LeGates, Philips, Morrison, Thompson, Puche, Gould, Rothstein, Wong, Monteiro: "Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 47, pp. E7580-E7589, (2016) (PubMed).

Riku, Watanabe, Yoshida, Mimuro, Iwasaki, Masuda, Ishigaki, Katsuno, Sobue: "Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis." in: Journal of neuropathology and experimental neurology, (2016) (PubMed).

Porta, Kwong, Trojanowski, Lee: "Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 380-7, (2015) (PubMed).

Zeng, Wang, Merillat, N Minakawa, Perkins, Ramani, Tallaksen-Greene, Costa, Albin, Paulson: "Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3." in: Neurobiology of disease, Vol. 82, pp. 281-8, (2015) (PubMed).

Ceballos-Diaz, Rosario, Park, Chakrabarty, Sacino, Cruz, Siemienski, Lara, Moran, Ravelo, Golde, McFarland: "Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice." in: Molecular neurodegeneration, Vol. 10, pp. 25, (2015) (PubMed).

Satoh, Tabunoki, Ishida, Saito, Arima: "Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains." in: Neuropathology and applied neurobiology, Vol. 39, Issue 7, pp. 817-30, (2014) (PubMed).

Aliases for Ubiquilin 2 抗体

ubiquilin 2 (UBQLN2) 抗体
ubiquilin 2 (Ubqln2) 抗体
ALS15 抗体
CHAP1 抗体
Chap1 抗体
DSK2 抗体
Dsk2 抗体
HRIHFB2157 抗体
N4BP4 抗体
Plic-2 抗体
PLIC2 抗体
Plic2 抗体
RGD1563566 抗体
UBQLN2 抗体
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