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Ubiquilin 2 抗体 (AA 555-624)

UBQLN2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5F5 unconjugated
产品编号 ABIN565449
发货至: 中国
  • 抗原 See all Ubiquilin 2 (UBQLN2) 抗体
    Ubiquilin 2 (UBQLN2)
    抗原表位
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 555-624
    适用
    • 59
    • 12
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 55
    • 4
    小鼠
    克隆类型
    • 56
    • 3
    单克隆
    标记
    • 23
    • 7
    • 7
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ubiquilin 2 antibody is un-conjugated
    应用范围
    • 40
    • 33
    • 21
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    原理
    Mouse monoclonal antibody raised against a partial recombinant UBQLN2.
    序列
    PNQQFIQQMV QALAGANAPQ LPNPEVRFQQ QLEQLNAMGF LNREANLQAL IATGGDINAA IERLLGSQPS
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    UBQLN2 (NP_038472, 555 a.a. ~ 624 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    5F5
    亚型
    IgG2a
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Riku, Watanabe, Yoshida, Mimuro, Iwasaki, Masuda, Ishigaki, Katsuno, Sobue: "Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis." in: Journal of neuropathology and experimental neurology, (2016) (PubMed).

    Porta, Kwong, Trojanowski, Lee: "Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 380-7, (2015) (PubMed).

    Zeng, Wang, Merillat, N Minakawa, Perkins, Ramani, Tallaksen-Greene, Costa, Albin, Paulson: "Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3." in: Neurobiology of disease, Vol. 82, pp. 281-8, (2015) (PubMed).

    Satoh, Tabunoki, Ishida, Saito, Arima: "Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains." in: Neuropathology and applied neurobiology, Vol. 39, Issue 7, pp. 817-30, (2014) (PubMed).

    Riku, Watanabe, Yoshida, Tatsumi, Mimuro, Iwasaki, Katsuno, Iguchi, Masuda, Senda, Ishigaki, Udagawa, Sobue: "Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis." in: JAMA neurology, Vol. 71, Issue 2, pp. 172-9, (2014) (PubMed).

    Farg, Sundaramoorthy, Sultana, Yang, Atkinson, Levina, Halloran, Gleeson, Blair, Soo, King, Atkin: "C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking." in: Human molecular genetics, Vol. 23, Issue 13, pp. 3579-95, (2014) (PubMed).

    Konno, Tada, Shiga, Tsujino, Eguchi, Masuda-Suzukake, Hasegawa, Nishizawa, Onodera, Kakita, Takahashi: "C9ORF72 repeat-associated non-ATG-translated polypeptides are distributed independently of TDP-43 in a Japanese patient with c9ALS." in: Neuropathology and applied neurobiology, Vol. 40, Issue 6, pp. 783-8, (2014) (PubMed).

    Bieniek, Murray, Rutherford, Castanedes-Casey, DeJesus-Hernandez, Liesinger, Baker, Boylan, Rademakers, Dickson: "Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion." in: Acta neuropathologica, Vol. 125, Issue 2, pp. 289-302, (2013) (PubMed).

    Murray, Bieniek, Banks Greenberg, DeJesus-Hernandez, Rutherford, van Blitterswijk, Niemantsverdriet, Ash, Gendron, Kouri, Baker, Goodman, Petrucelli, Rademakers, Dickson: "Progressive amnestic dementia, hippocampal sclerosis, and mutation in C9ORF72." in: Acta neuropathologica, Vol. 126, Issue 4, pp. 545-54, (2013) (PubMed).

    Brettschneider, Van Deerlin, Robinson, Kwong, Lee, Ali, Safren, Monteiro, Toledo, Elman, McCluskey, Irwin, Grossman, Molina-Porcel, Lee, Trojanowski: "Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion." in: Acta neuropathologica, Vol. 123, Issue 6, pp. 825-39, (2012) (PubMed).

    Al-Sarraj, King, Troakes, Smith, Maekawa, Bodi, Rogelj, Al-Chalabi, Hortobágyi, Shaw: "p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS." in: Acta neuropathologica, Vol. 122, Issue 6, pp. 691-702, (2011) (PubMed).

  • 抗原
    Ubiquilin 2 (UBQLN2)
    别名
    UBQLN2 (UBQLN2 产品)
    别名
    ALS15 antibody, CHAP1 antibody, DSK2 antibody, N4BP4 antibody, PLIC2 antibody, Chap1 antibody, Dsk2 antibody, HRIHFB2157 antibody, Plic-2 antibody, Plic2 antibody, RGD1563566 antibody, UBQLN2 antibody, ubiquilin 2 antibody, UBQLN2 antibody, Ubqln2 antibody
    背景
    Full Gene Name: ubiquilin 2
    Synonyms: CHAP1,CHAP1/DSK2,Dsk2,HRIHFB2157,LIC-2,N4BP4,PLIC-2,PLIC2,RIHFB2157
    基因ID
    29978
    NCBI登录号
    NM_013444
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