ube3a 抗体
(Ubiquitin Protein Ligase E3A (ube3a))
This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ube3a 抗体 (AA 51-150) | 人 | 小鼠 Monoclonal |
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| ube3a 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ube3a 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| ube3a 抗体 (AA 1-860) | 人 | 兔 Polyclonal |
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| ube3a 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ube3a 抗体 (AA 300-590) | 人 | 兔 Polyclonal |
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| ube3a 抗体 | 人 | 小鼠 Monoclonal |
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| ube3a 抗体 (AA 83-234) | 人 | 兔 Polyclonal |
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| Recombinant ube3a 抗体 | 人 | 兔 Monoclonal |
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| ube3a 抗体 | 人 | 兔 Polyclonal |
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| ube3a 抗体 (Middle Region) | 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, 斑马鱼, Cow | 兔 Polyclonal |
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| ube3a 抗体 (AA 180-229) | 人, 猴, 大鼠, 斑马鱼, Bat, Drosophila melanogaster | 兔 Polyclonal |
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| ube3a 抗体 (C-Term) | 人, 小鼠, 猴, 大鼠, 兔, 犬, 豚鼠, 马, 斑马鱼, Cow, 小鸡, Bat, Pig | 兔 Polyclonal |
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| ube3a 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| ube3a 抗体 (AA 75-125) | 人, 小鼠 | 兔 Polyclonal |
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| ube3a 抗体 (AA 400-450) | 人, 小鼠 | 兔 Polyclonal |
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| ube3a 抗体 (AA 158-407) | 人 | 兔 Polyclonal |
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| ube3a 抗体 (AA 701-800) | 人 | 兔 Polyclonal |
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| ube3a 抗体 (AA 701-800) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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| ube3a 抗体 (AA 701-800) (Biotin) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ISt (Immunostaining: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
1 reference - 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2F6
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 51-150
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB4440
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 836-865, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-860
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 300-590
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 83-234
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB4775
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, 斑马鱼, Cow
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 75-125
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 400-450
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 158-407
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 701-800
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 701-800
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 701-800
Latest Publications for our ube3a 抗体
: "Cognition and Synaptic-Plasticity Related Changes in Aged Rats Supplemented with 8- and 10-Carbon Medium Chain Triglycerides." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160159, (2017) (PubMed).
: "A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging." in: Neurobiology of learning and memory, Vol. 115, pp. 58-67, (2014) (PubMed).
: "E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis." in: Blood, Vol. 120, Issue 4, pp. 822-32, (2012) (PubMed).
: "Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a." in: Human molecular genetics, Vol. 21, Issue 13, pp. 3001-12, (2012) (PubMed).
: "Spatial and temporal silencing of the human maternal UBE3A gene." in: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, Vol. 16, Issue 6, pp. 587-91, (2012) (PubMed).
: "Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome." in: PLoS ONE, Vol. 6, Issue 12, pp. e27221, (2011) (PubMed).
: "Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 12, pp. 5611-6, (2010) (PubMed).
: "Isoform-specific degradation of PR-B by E6-AP is critical for normal mammary gland development." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 11, pp. 2099-113, (2010) (PubMed).
: "E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation." in: Journal of virology, Vol. 82, Issue 21, pp. 10408-17, (2008) (PubMed).
: "Thiothymidine plus low-dose UVA kills hyperproliferative human skin cells independently of their human papilloma virus status." in: Molecular cancer therapeutics, Vol. 6, Issue 9, pp. 2487-95, (2007) (PubMed).
: "A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging." in: Neurobiology of learning and memory, Vol. 115, pp. 58-67, (2014) (PubMed).
: "E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis." in: Blood, Vol. 120, Issue 4, pp. 822-32, (2012) (PubMed).
: "Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a." in: Human molecular genetics, Vol. 21, Issue 13, pp. 3001-12, (2012) (PubMed).
: "Spatial and temporal silencing of the human maternal UBE3A gene." in: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, Vol. 16, Issue 6, pp. 587-91, (2012) (PubMed).
: "Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome." in: PLoS ONE, Vol. 6, Issue 12, pp. e27221, (2011) (PubMed).
: "Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 12, pp. 5611-6, (2010) (PubMed).
: "Isoform-specific degradation of PR-B by E6-AP is critical for normal mammary gland development." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 11, pp. 2099-113, (2010) (PubMed).
: "E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation." in: Journal of virology, Vol. 82, Issue 21, pp. 10408-17, (2008) (PubMed).
: "Thiothymidine plus low-dose UVA kills hyperproliferative human skin cells independently of their human papilloma virus status." in: Molecular cancer therapeutics, Vol. 6, Issue 9, pp. 2487-95, (2007) (PubMed).
Aliases for ube3a 抗体
ubiquitin protein ligase E3A (UBE3A) 抗体ubiquitin-protein ligase E3A (ube3a) 抗体
ubiquitin-protein ligase E3A (LOC100194730) 抗体
ubiquitin protein ligase E3A (Ube3a) 抗体
ubiquitin protein ligase E3A (ube3a) 抗体
Ubiquitin protein ligase E3A (Ube3a) 抗体
ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog (ube3a.S) 抗体
ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) (ube3a) 抗体
ubiquitin protein ligase E3A (Eint_040430) 抗体
4732496B02 抗体
5830462N02Rik 抗体
A130086L21Rik 抗体
ANCR 抗体
AS 抗体
As 抗体
CG6190 抗体
das 抗体
DDBDRAFT_0188760 抗体
DDBDRAFT_0302447 抗体
DDB_0188760 抗体
DDB_0302447 抗体
Dmel\\CG6190 抗体
Dube3a 抗体
dUBE3A 抗体
dube3A 抗体
dube3a 抗体
E6-AP 抗体
EPVE6AP 抗体
HPVE6A 抗体
Hpve6a 抗体
im:7140733 抗体
MGC69536 抗体
mKIAA4216 抗体
ube3a 抗体
UBE3A 抗体
UME3A 抗体
zgc:92173 抗体
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