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ube3a 抗体 (AA 400-450)

The 兔 多克隆 anti-ube3a antibody (ABIN7449675) specifically detects ube3a in WB 和 IP. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7449675
发货至: 中国
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Quick Overview for ube3a 抗体 (AA 400-450) (ABIN7449675)

抗原

See all ube3a 抗体
ube3a (Ubiquitin Protein Ligase E3A (ube3a))

适用

  • 64
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  • 1
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人, 小鼠

宿主

  • 51
  • 13

克隆类型

  • 47
  • 17
多克隆

标记

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  • 5
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This ube3a antibody is un-conjugated

应用范围

  • 37
  • 17
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  • 16
  • 16
  • 13
  • 13
  • 10
  • 6
  • 4
  • 3
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 8
    • 5
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    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-450

    原理

    Rabbit anti-E6AP Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 400 and 450

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:1,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    ube3a (Ubiquitin Protein Ligase E3A (ube3a))

    别名

    E6AP

    背景

    Background: E6AP is an E3 ubiquitin ligase. Inheritance of a mutant maternal copy of this gene results in Angelman syndrome (AS) which is characterized by severe mental retardation, seizures, ataxia, and EEG abnormalities. E6AP interacts with the type 16 and 18 human papillomavirus E6 oncoprotein which results in the targeting of p53 for degradation via the ubiquitin-proteasome system.

    基因ID

    7337

    NCBI登录号

    NP_000453

    UniProt

    Q05086

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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