-
- 抗原 See all ube3a 抗体
- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
-
抗原表位
- AA 83-234
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ube3a antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Ubiquitin-protein ligase E3A protein (83-234AA)
- 亚型
- IgG
- Top Product
- Discover our top product ube3a Primary Antibody
-
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 51-150) antibody
ube3a 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 836-865), (C-Term) antibodyube3a 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB4440 unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (C-Term) antibodyube3a 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 300-590) antibodyube3a 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (Middle Region) antibodyube3a 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, 斑马鱼, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a 适用: 人 IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a 适用: 人 WB, IHC, IF/ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 158-407) antibodyube3a 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
- 别名
- UBE3A (ube3a 产品)
- 别名
- ANCR antibody, AS antibody, E6-AP antibody, EPVE6AP antibody, HPVE6A antibody, DDBDRAFT_0188760 antibody, DDBDRAFT_0302447 antibody, DDB_0188760 antibody, DDB_0302447 antibody, ube3a antibody, im:7140733 antibody, zgc:92173 antibody, 4732496B02 antibody, 5830462N02Rik antibody, A130086L21Rik antibody, Hpve6a antibody, mKIAA4216 antibody, As antibody, CG6190 antibody, Dmel\\CG6190 antibody, Dube3a antibody, UBE3A antibody, dUBE3A antibody, das antibody, dube3A antibody, dube3a antibody, MGC69536 antibody, UME3A antibody, ubiquitin protein ligase E3A antibody, ubiquitin-protein ligase E3A antibody, Ubiquitin protein ligase E3A antibody, ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog antibody, ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) antibody, UBE3A antibody, ube3a antibody, LOC100194730 antibody, Ube3a antibody, ube3a.S antibody, Eint_040430 antibody
- 背景
-
Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Catalyzes the high-risk human papilloma virus E6-mediated ubiquitination of p53/TP53, contributing to the neoplastic progression of cells infected by these viruses. Additionally, may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. Finally, UBE3A also promotes its own degradation in vivo. Plays an important role in the regulation of the circadian clock: involved in the ubiquitination of the core clock component ARNTL/BMAL1, leading to its proteasomal degradation (PubMed:24728990).
Aliases: ANCR antibody, Angelman syndrome antibody, AS antibody, CTCL tumor antigen se37 2 antibody, CTCL tumor antigen se37-2 antibody, E6 AP antibody, E6AP antibody, E6AP ubiquitin protein ligase antibody, E6AP ubiquitin-protein ligase antibody, EPVE6AP antibody, FLJ26981 antibody, HECT-type ubiquitin transferase E3A antibody, HPVE6A antibody, Human papilloma virus E6 associated protein Angelman syndrome antibody, Human papilloma virus E6 associated protein antibody, Human papillomavirus E6-associated protein antibody, NY REN 54 antigen antibody, Oncogenic protein associated protein E6 AP antibody, Oncogenic protein associated protein E6AP antibody, Oncogenic protein-associated protein E6-AP antibody, Renal carcinoma antigen NY REN 54 antibody, Renal carcinoma antigen NY-REN-54 antibody, UBE 3A antibody, Ube3a antibody, UBE3A protein antibody, UBE3A_HUMAN antibody, Ubiquitin protein ligase E3A antibody, Ubiquitin-protein ligase E3A antibody
- UniProt
- Q05086
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
-
You are here:
