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Ubiquilin 2 抗体

(Ubiquilin 2 (UBQLN2))
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases\; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein. [provided by RefSeq, Oct 2009].

Active filters:

  • 抗原: Ubiquilin 2 (UBQLN2)
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6852543
Ubiquilin 2 抗体 (Alexa Fluor 750) UBQLN2 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6868606
Ubiquilin 2 抗体 (Biotin) UBQLN2 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6844416
Ubiquilin 2 抗体 (Alexa Fluor 647) UBQLN2 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6828353
Ubiquilin 2 抗体 (Alexa Fluor 594) UBQLN2 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6812290
Ubiquilin 2 抗体 (Alexa Fluor 488) UBQLN2 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN5565427
Ubiquilin 2 抗体 (AA 1-624) (APC) UBQLN2 · Primary Antibody 人 兔 Polyclonal
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • 150 μg
发货至: 中国
ABIN5565426
Ubiquilin 2 抗体 (AA 1-624) UBQLN2 · Primary Antibody 人 兔 Polyclonal
  • EIA (Enzyme Immunoassay: 所列应用)
  • RIA (Radioimmunoassay: 所列应用)
  • 150 μg
发货至: 中国
ABIN5565429
Ubiquilin 2 抗体 (AA 1-624) (FITC) UBQLN2 · Primary Antibody 人 兔 Polyclonal
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • 150 μg
发货至: 中国
ABIN5565428
Ubiquilin 2 抗体 (AA 1-624) (Biotin) UBQLN2 · Primary Antibody 人 兔 Polyclonal
  • EIA (Enzyme Immunoassay: 所列应用)
  • RIA (Radioimmunoassay: 所列应用)
  • 150 μg
发货至: 中国
ABIN5565431
Ubiquilin 2 抗体 (AA 1-624) (PE) UBQLN2 · Primary Antibody 人 兔 Polyclonal
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • 150 μg
发货至: 中国
ABIN5565430
Ubiquilin 2 抗体 (AA 1-624) (PerCP) UBQLN2 · Primary Antibody 人 兔 Polyclonal
  • FACS (Flow Cytometry: 所列应用)
  • 150 μg
发货至: 中国
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 750
产品编号 ABIN6852543
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
产品编号 ABIN6868606
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 647
产品编号 ABIN6844416
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 594
产品编号 ABIN6828353
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 488
产品编号 ABIN6812290
Primary Antibody
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
APC
抗原表位
AA 1-624
产品编号 ABIN5565427
Primary Antibody
  • EIA (Enzyme Immunoassay: 所列应用)
  • RIA (Radioimmunoassay: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗原表位
AA 1-624
产品编号 ABIN5565426
Primary Antibody
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
FITC
抗原表位
AA 1-624
产品编号 ABIN5565429
Primary Antibody
  • EIA (Enzyme Immunoassay: 所列应用)
  • RIA (Radioimmunoassay: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
抗原表位
AA 1-624
产品编号 ABIN5565428
Primary Antibody
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
PE
抗原表位
AA 1-624
产品编号 ABIN5565431
Primary Antibody
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
PerCP
抗原表位
AA 1-624
产品编号 ABIN5565430

Latest Publications for our Ubiquilin 2 抗体

Alexander, Ghanbari Niaki, Zhang, Sarkar, Liu, Nirujogi, Pandey, Myong, Wang: "Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 49, pp. E11485-E11494, (2019) (PubMed).

Sharkey, Safren, Pithadia, Gerson, Dulchavsky, Fischer, Patel, Lantis, Ashraf, Kim, Meliki, Minakawa, Barmada, Ivanova, Paulson: "Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 44, pp. E10495-E10504, (2018) (PubMed).

Yau, Doerner, Castellanos, Haakonsen, Werner, Wang, Yang, Martinez-Martin, Matsumoto, Dixit, Rape: "Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control." in: Cell, Vol. 171, Issue 4, pp. 918-933.e20, (2017) (PubMed).

Hjerpe, Bett, Keuss, Solovyova, McWilliams, Johnson, Sahu, Varghese, Wood, Wightman, Osborne, Bates, Glickman, Trost, Knebel, Marchesi, Kurz: "UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome." in: Cell, Vol. 166, Issue 4, pp. 935-49, (2016) (PubMed).

Le, Chang, Kovlyagina, Georgiou, Safren, Braunstein, Kvarta, Van Dyke, LeGates, Philips, Morrison, Thompson, Puche, Gould, Rothstein, Wong, Monteiro: "Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 47, pp. E7580-E7589, (2016) (PubMed).

Riku, Watanabe, Yoshida, Mimuro, Iwasaki, Masuda, Ishigaki, Katsuno, Sobue: "Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis." in: Journal of neuropathology and experimental neurology, (2016) (PubMed).

Porta, Kwong, Trojanowski, Lee: "Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 380-7, (2015) (PubMed).

Zeng, Wang, Merillat, N Minakawa, Perkins, Ramani, Tallaksen-Greene, Costa, Albin, Paulson: "Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3." in: Neurobiology of disease, Vol. 82, pp. 281-8, (2015) (PubMed).

Ceballos-Diaz, Rosario, Park, Chakrabarty, Sacino, Cruz, Siemienski, Lara, Moran, Ravelo, Golde, McFarland: "Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice." in: Molecular neurodegeneration, Vol. 10, pp. 25, (2015) (PubMed).

Satoh, Tabunoki, Ishida, Saito, Arima: "Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains." in: Neuropathology and applied neurobiology, Vol. 39, Issue 7, pp. 817-30, (2014) (PubMed).

Aliases for Ubiquilin 2 抗体

ubiquilin 2 (UBQLN2) 抗体
ubiquilin 2 (Ubqln2) 抗体
ALS15 抗体
CHAP1 抗体
Chap1 抗体
DSK2 抗体
Dsk2 抗体
HRIHFB2157 抗体
N4BP4 抗体
Plic-2 抗体
PLIC2 抗体
Plic2 抗体
RGD1563566 抗体
UBQLN2 抗体
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