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UBE2M 产品

(Ubiquitin-Conjugating Enzyme E2M (ube2m))

Categories

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq, Jul 2008].

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Featured UBE2M Categories

UBE2M 抗体

High quality antibodies with extensive validation data.

UBE2M 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended UBE2M 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (7)
Cat. No. ABIN2775686
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (4)
Cat. No. ABIN563918
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IHC, ICC
Validations
  • (3)
Cat. No. ABIN6265852
Quantity 100 μL
Datasheet Datasheet

Recommended UBE2M ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730521
Quantity 96 tests
Datasheet Datasheet

Recommended UBE2M 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN1098637
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324388
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3075213
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our UBE2M Products

Liu, Reitsma, Mamrosh, Zhang, Straube, Deshaies: "Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression." in: Molecular cell, Vol. 69, Issue 5, pp. 773-786.e6, (2019) (PubMed).

Sun, Boxer, Ransohoff, Siprashvili, Qu, Lopez-Pajares, Hollmig, Khavari: "CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation." in: Genes & development, Vol. 29, Issue 21, pp. 2225-30, (2015) (PubMed).

Miller, Lau, Grouios, Mollica, Barrios-Rodiles, Liu, Datti, Morris, Wrana, Attisano: "Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway." in: Molecular systems biology, Vol. 5, pp. 315, (2009) (PubMed).

Kolokoltsova, Domina, Kolokoltsov, Davey, Weaver, Watowich: "Alphavirus production is inhibited in neurofibromin 1-deficient cells through activated RAS signalling." in: Virology, Vol. 377, Issue 1, pp. 133-42, (2008) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Danet, Luongo, Butler, Lu, Tenner, Simon, Bonnet: "C1qRp defines a new human stem cell population with hematopoietic and hepatic potential." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 16, pp. 10441-5, (2002) (PubMed).

Nepomuceno, Ruiz, Park, Tenner: "C1qRP is a heavily O-glycosylated cell surface protein involved in the regulation of phagocytic activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 6, pp. 3583-9, (1999) (PubMed).

Tenner: "C1q receptors: regulating specific functions of phagocytic cells." in: Immunobiology, Vol. 199, Issue 2, pp. 250-64, (1999) (PubMed).

Nepomuceno, Tenner: "C1qRP, the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 4, pp. 1929-35, (1998) (PubMed).

Nepomuceno, Henschen-Edman, Burgess, Tenner: "cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro." in: Immunity, Vol. 6, Issue 2, pp. 119-29, (1997) (PubMed).

Synonyms and alternative names related to UBE2M

ubiquitin conjugating enzyme E2M (ube2m), ubiquitin-conjugating enzyme E2M (LOC692934), ubiquitin conjugating enzyme E2 M (UBE2M), NEDD8-conjugating enzyme (ube2m), ubiquitin-conjugating enzyme E2M (Ube2m), ubiquitin conjugating enzyme E2M S homeolog (ube2m.S), 2510040H03Rik, DDBDRAFT_0204633, DDBDRAFT_0238042, DDB_0204633, DDB_0238042, hUbc12, UBC-RS2, Ubc-rs2, UBC12

Protein level used designations for UBE2M

  • NEDD8 carrier protein
  • NEDD8 protein ligase
  • NEDD8-conjugating enzyme Ubc12
  • ubiquitin-conjugating enzyme E2M (UBC12 homolog)
  • ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
  • ubiquitin-conjugating enzyme E2M
  • ubiquitin-conjugating enzyme E2 M
  • ubiquitin carrier protein M
  • ubiquitin-protein ligase M
  • yeast UBC12 homolog
  • UBC12 homolog, yeast
  • ubiquitin C, related sequence 2
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