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UBE2V1 产品

(Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

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Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Apr 2012].

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Featured UBE2V1 Categories

UBE2V1 抗体

High quality antibodies with extensive validation data.

UBE2V1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Cat. No. ABIN7245950
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Cat. No. ABIN6149827
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Cat. No. ABIN7125601
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Latest Publications for our UBE2V1 Products

Davoodi, Lin, Kelly, Liston, MacKenzie: "Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40622-8, (2004) (PubMed).

Vogel, Fitzgerald, Fenton: "TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression." in: Molecular interventions, Vol. 3, Issue 8, pp. 466-77, (2004) (PubMed).

Akira, Takeda: "Toll-like receptor signalling." in: Nature reviews. Immunology, Vol. 4, Issue 7, pp. 499-511, (2004) (PubMed).

Liston, Fong, Korneluk: "The inhibitors of apoptosis: there is more to life than Bcl2." in: Oncogene, Vol. 22, Issue 53, pp. 8568-80, (2003) (PubMed).

Deng, Wang, Spencer, Yang, Braun, You, Slaughter, Pickart, Chen: "Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain." in: Cell, Vol. 103, Issue 2, pp. 351-61, (2000) (PubMed).

Long: "A new function evolved from gene fusion." in: Genome research, Vol. 10, Issue 11, pp. 1655-7, (2000) (PubMed).

Thomson, Lozano, Loukili, Carrió, Serras, Cormand, Valeri, Díaz, Abril, Burset, Merino, Macaya, Corominas, Guigó: "Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene." in: Genome research, Vol. 10, Issue 11, pp. 1743-56, (2000) (PubMed).

Roy, Mahadevan, McLean, Shutler, Yaraghi, Farahani, Baird, Besner-Johnston, Lefebvre, Kang: "The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy." in: Cell, Vol. 80, Issue 1, pp. 167-78, (1995) (PubMed).

Synonyms and alternative names related to UBE2V1

ubiquitin conjugating enzyme E2 V1 (UBE2V1), ubiquitin-conjugating enzyme E2 variant 1 (ube2v1), ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1), ubiquitin-conjugating enzyme E2 variant 1 (Ube2v1), ubiquitin conjugating enzyme E2 V1 (Ube2v1), 0610011J09Rik, AI256840, CIR1, CROC-1, CROC-1B, CROC1, D7Bwg1382e, UBE2V, UEV-1, UEV1, UEV1A

Protein level used designations for UBE2V1

  • ubiquitin-conjugating enzyme E2 variant 1
  • DNA-binding protein
  • TRAF6-regulated IKK activator 1 beta Uev1A
  • UEV-1
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