UBE3B 产品
(Ubiquitin Protein Ligase E3B (UBE3B))
Categories
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2012].
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Featured UBE3B Categories
Recommended UBE3B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6265855
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6740821
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
- (1)
Cat. No.
ABIN2781245
Quantity
100 μL
Datasheet
Datasheet
Recommended UBE3B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324430
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3096166
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3137222
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our UBE3B Products
: "Gene expression profile associated with postnatal development of pyramidal neurons in the human prefrontal cortex implicates ubiquitin ligase E3 in the pathophysiology of schizophrenia onset." in: Journal of psychiatric research, Vol. 102, pp. 110-117, (2019) (PubMed).: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).
Synonyms and alternative names related to UBE3B
ubiquitin protein ligase E3B (UBE3B), ubiquitin protein ligase E3B (ube3b), ubiquitin-protein ligase E3B (LOC581811), ubiquitin protein ligase E3B L homeolog (ube3b.L), ubiquitin protein ligase E3B (Ube3b), AI449831, AU020130, BPIDS, si:dkey-189p24.3Protein level used designations for UBE3B
- ubiquitin-protein ligase E3B
- ubiquitin protein ligase E3B
- ubiquitin-protein ligase E3B-like
- ubiquitin protein ligase E3
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