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UBE2D2 产品

(Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [provided by RefSeq, Jul 2008].

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Featured UBE2D2 Categories

UBE2D2 抗体

High quality antibodies with extensive validation data.

UBE2D2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended UBE2D2 抗体

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Cat. No. ABIN521212
Quantity 100 μg
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Cat. No. ABIN7174438
Quantity 100 μg
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Reactivity Human, Mouse
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Cat. No. ABIN1385976
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Recommended UBE2D2 蛋白

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Cat. No. ABIN7125610
Quantity 50 μg
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Cat. No. ABIN1324344
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Latest Publications for our UBE2D2 Products

Lewis, Vyse, Shields, Boeltz, Gordon, Spector, Lehner, Walczak, Vyse: "UBE2L3 polymorphism amplifies NF-?B activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases." in: American journal of human genetics, Vol. 96, Issue 2, pp. 221-34, (2015) (PubMed).

Peters, Rees, Hardwick, Hardwick, Vowler, Ong, Zhang, Save, ODonovan, Rassl, Alderson, Caldas, Fitzgerald: "A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia." in: Gastroenterology, Vol. 139, Issue 6, pp. 1995-2004.e15, (2010) (PubMed).

Desforges, Lacey, Glazier, Greenwood, Mynett, Speake, Sibley: "SNAT4 isoform of system A amino acid transporter is expressed in human placenta." in: American journal of physiology. Cell physiology, Vol. 290, Issue 1, pp. C305-12, (2005) (PubMed).

Synonyms and alternative names related to UBE2D2

ubiquitin conjugating enzyme E2 D2 (UBE2D2), ubiquitin-conjugating enzyme E2D 2A (Ube2d2a), ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) (ube2d2), ubiquitin-conjugating enzyme E2D 2 (Ube2d2), ubiquitin conjugating enzyme E2 D3 (UBE2D3), ubiquitin conjugating enzyme E2 D2 (Ube2d2), 1500034D03Rik, E2(17)KB2, E217kB, PUBC1, Ubc2e, UBC4, ubc4, UBC4/5, UBCH5B, Ube2d2, ube2d2, zgc:55886

Protein level used designations for UBE2D2

  • p53-regulated ubiquitin-conjugating enzyme 1
  • ubiquitin carrier protein D2
  • ubiquitin-conjugating enzyme E2 D2
  • ubiquitin-conjugating enzyme E2-17 kDa 2
  • ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5)
  • ubiquitin-protein ligase D2
  • E2(17)KB 2
  • ubiquitin conjugating enzyme 2e
  • ubiquitin-conjugating enzyme E2(17)KB 2
  • ubiquitin-conjugating enzyme E2D 2
  • ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
  • ubc2e ubiquitin conjugating enzyme
  • UB2D2
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