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TRPV4 产品

(Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].

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Featured TRPV4 Categories

TRPV4 抗体

High quality antibodies with extensive validation data.

TRPV4 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TRPV4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TRPV4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN2776284
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC, LCI
Validations
  • (5)
Cat. No. ABIN7043852
Quantity 25 μL
Datasheet Datasheet
Reactivity Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rat
Application WB, IHC, IF, IHC (p), IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN1049441
Quantity 50 μg
Datasheet Datasheet

Recommended TRPV4 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6974723
Quantity 96 tests
Datasheet Datasheet

Recommended TRPV4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3118242
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3137157
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TRPV4 Products

Liebe, Liebe, Sponder, Mergler, Stumpff: "Effects of butyrate- on ruminal Ca2+ transport: evidence for the involvement of apically expressed TRPV3 and TRPV4 channels." in: Pflugers Archiv : European journal of physiology, Vol. 474, Issue 3, pp. 315-342, (2022) (PubMed).

Sakakibara, Sakakibara, Kusumoto, Takeda, Hasegawa, Akashi, Minamikawa, Hashikawa, Terashi, Komori et al.: "Upregulated Expression of Transient Receptor Potential Cation Channel Subfamily V Receptors in Mucosae of Patients with Oral Squamous Cell Carcinoma and Patients with a History of Alcohol Consumption ..." in: PLoS ONE, Vol. 12, Issue 1, pp. e0169723, (2017) (PubMed).

Wheeler, Smith, Ottolini, Barker, Purohit, Grippo, Gaykema, Spano, Beenhakker, Kucenas, Patel, Deppmann, Güler: "Genetically targeted magnetic control of the nervous system." in: Nature neuroscience, Vol. 19, Issue 5, pp. 756-61, (2016) (PubMed).

Singh, Ram, Kandasamy, Thangamalai, Choudhary, Dash, Kumar, Parida, Singh, Mishra: "Molecular and functional characterization of TRPV4 channels in pregnant and nonpregnant mouse uterus." in: Life sciences, Vol. 122, pp. 51-8, (2015) (PubMed).

Scheraga, Abraham, Niese, Southern, Grove, Hite, McDonald, Hamilton, Olman: "TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 1, pp. 428-36, (2015) (PubMed).

Rahaman, Grove, Paruchuri, Southern, Abraham, Niese, Scheraga, Ghosh, Thodeti, Zhang, Moran, Schilling, Tschumperlin, Olman: "TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice." in: The Journal of clinical investigation, Vol. 124, Issue 12, pp. 5225-38, (2014) (PubMed).

Sampat, Dermksian, Oungoulian, Winchester, Bulinski, Ateshian, Hung: "Applied osmotic loading for promoting development of engineered cartilage." in: Journal of biomechanics, Vol. 46, Issue 15, pp. 2674-81, (2013) (PubMed).

Lunov, Zablotskii, Syrovets, Buechele, Schmidt, Dejneka, Le Roy, Dumas-Bouchiat, Dempsey, Simmet: "WITHDRAWN: Static High-Gradient Magnetic Fields Activate Transient Receptor Potential Vanilloid 4 (TRPV4) Ion Channels Enabling Remote Control of Cell Function." in: The Journal of biological chemistry, (2013) (PubMed).

Butenko, Dzamba, Benesova, Honsa, Benfenati, Rusnakova, Ferroni, Anderova: "The increased activity of TRPV4 channel in the astrocytes of the adult rat hippocampus after cerebral hypoxia/ischemia." in: PLoS ONE, Vol. 7, Issue 6, pp. e39959, (2012) (PubMed).

Zhang, Catalán, Melvin: "TRPV4 activation in mouse submandibular gland modulates Ca2+ influx and salivation." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 303, Issue 12, pp. G1365-72, (2012) (PubMed).

Synonyms and alternative names related to TRPV4

transient receptor potential cation channel, subfamily V, member 4 (trpv4), transient receptor potential cation channel subfamily V member 4 (TRPV4), transient receptor potential cation channel, subfamily V, member 4 (Trpv4), 0610033B08Rik, CMT2C, HMSN2C, OTRPC4, Otrpc4, SMAL, SPSMA, SSQTL1, TRP12, Trp12, VR-OAC, VRL-2, VRL2, VROAC, Vroac, wu:fp52e02

Protein level used designations for TRPV4

  • transient receptor potential cation channel subfamily V member 4
  • transient receptor potential cation channel, subfamily V, member 4
  • transient receptor potential cation channel subfamily V member 4-like
  • OSM9-like transient receptor potential channel 4
  • osm-9-like TRP channel 4
  • osmosensitive transient receptor potential channel 4
  • transient receptor potential protein 12
  • vanilloid receptor-like channel 2
  • vanilloid receptor-related osmotically activated channel
  • vanilloid receptor-like protein 2
  • vanilloid receptor-related osmotically-activated channel
  • VR-OAC
  • transient receptor potential cation channel, subfamily 5, member 4
  • vanilloid receptor-related osmotically activated channel (Vroac)
  • vanilloid receptor-related osmotically activated channel protein
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