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TRPV4 抗体 (AA 301-400)

Name: TRPV4 抗体 (AA 301-400)
SKU: ABIN873245
Availability: OutOfStock

TRPV4 适用: 人, Cow WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat spinal cord tissue labeled with Rabbit Anti TRPV4/TRP12 Polyclonal Antibody, Unconjugated (ABIN873245) at 1:200 followed by conjugation to the secondary antibody and DAB staining (TRPV4 抗体 (AA 301-400))

IHC

1 image

(1 reference)

产品编号 ABIN873245

发货至: 中国

Datasheet as PDF

抗原 See all TRPV4 抗体

TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
抗原表位
15

14

9

5

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 301-400
适用
61

26

25

21

6

5

3

2

2

2

1

1

1

1
人, Cow
宿主
61

2

1

1
兔
Compatible Secondaries
克隆类型
64

1
多克隆
标记
31

4

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1
This TRPV4 antibody is un-conjugated
应用范围
50

24

16

14

6

6

3

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

交叉反应

Cow, 人

预测反应

Mouse,Rat,Dog,Cow,Pig,Chicken

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human TRPV4

亚型

IgG

Top Product

Discover our top product TRPV4 Primary Antibody
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Middle Region) antibody
TRPV4 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (3rd Extracellular Loop), (AA 647-662) antibody
TRPV4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Internal Region) antibody
TRPV4 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 猴, Hamster, 马 WB, IHC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 853-871), (C-Term), (Intracellular) antibody
TRPV4 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 1-230) antibody
TRPV4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (C-Term) antibody
TRPV4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) antibody
TRPV4 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (N-Term) antibody
TRPV4 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 461-510) antibody
TRPV4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 719-768) antibody
TRPV4 适用: 人, 小鼠, 大鼠, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Sakakibara, Sakakibara, Kusumoto, Takeda, Hasegawa, Akashi, Minamikawa, Hashikawa, Terashi, Komori et al.: "Upregulated Expression of Transient Receptor Potential Cation Channel Subfamily V Receptors in Mucosae of Patients with Oral Squamous Cell Carcinoma and Patients with a History of Alcohol Consumption ..." in: PLoS ONE, Vol. 12, Issue 1, pp. e0169723, (2017) (PubMed).
抗原

TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))

别名

TRP12 (TRPV4 产品)

别名

wu:fp52e02 antibody, CMT2C antibody, HMSN2C antibody, OTRPC4 antibody, SMAL antibody, SPSMA antibody, SSQTL1 antibody, TRP12 antibody, VRL2 antibody, VROAC antibody, 0610033B08Rik antibody, Trp12 antibody, VR-OAC antibody, VRL-2 antibody, Otrpc4 antibody, Vroac antibody, transient receptor potential cation channel, subfamily V, member 4 antibody, transient receptor potential cation channel subfamily V member 4 antibody, trpv4 antibody, TRPV4 antibody, Trpv4 antibody

背景

Synonyms: SMAL, VRL2, BCYM3, CMT2C, SPSMA, TRP12, VROAC, HMSN2C, OTRPC4, SSQTL1, Transient receptor potential cation channel subfamily V member 4, TrpV4, Osm-9-like TRP channel 4, Transient receptor potential protein 12, Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2, VRL-2, Vanilloid receptor-related osmotically-activated channel, VR-OAC
Background: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH , citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.

基因ID

59341

UniProt

Q9HBA0

途径

Hormone Transport, Cell-Cell Junction Organization