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Tryptophan Hydroxylase 1 产品

(Tryptophan Hydroxylase 1 (TPH1))

Categories

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009].

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Featured Tryptophan Hydroxylase 1 Categories

Tryptophan Hydroxylase 1 抗体

High quality antibodies with extensive validation data.

Tryptophan Hydroxylase 1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Tryptophan Hydroxylase 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Tryptophan Hydroxylase 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (5)
Cat. No. ABIN6265687
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN5590052
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN390917
Quantity 400 μL
Datasheet Datasheet

Recommended Tryptophan Hydroxylase 1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970917
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970916
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960225
Quantity 96 tests
Datasheet Datasheet

Recommended Tryptophan Hydroxylase 1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125511
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323424
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323422
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Tryptophan Hydroxylase 1 Products

Qu, Yuan, Yu, Huang, Yang, Chen, Lai, Su, Zeng, Xie, Zhang: "Patchouli alcohol ameliorates dextran sodium sulfate-induced experimental colitis and suppresses tryptophan catabolism." in: Pharmacological research, Vol. 121, pp. 70-82, (2017) (PubMed).

Haycock, Kumer, Lewis, Vrana, Stockmeier: "A monoclonal antibody to tryptophan hydroxylase: applications and identification of the epitope." in: Journal of neuroscience methods, Vol. 114, Issue 2, pp. 205-12, (2002) (PubMed).

Joza, Susin, Daugas, Stanford, Cho, Li, Sasaki, Elia, Cheng, Ravagnan, Ferri, Zamzami, Wakeham, Hakem, Yoshida, Kong, Mak, Zúñiga-Pflücker, Kroemer, Penninger: "Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death." in: Nature, Vol. 410, Issue 6828, pp. 549-54, (2001) (PubMed).

Martinou, Green: "Breaking the mitochondrial barrier." in: Nature reviews. Molecular cell biology, Vol. 2, Issue 1, pp. 63-7, (2001) (PubMed).

Martínez, Knappskog, Haavik: "A structural approach into human tryptophan hydroxylase and its implications for the regulation of serotonin biosynthesis." in: Current medicinal chemistry, Vol. 8, Issue 9, pp. 1077-91, (2001) (PubMed).

Jiang, Yohrling, Schmitt, Vrana, Yohrling, Schmitt: "Identification of substrate orienting and phosphorylation sites within tryptophan hydroxylase using homology-based molecular modeling." in: Journal of molecular biology, Vol. 302, Issue 4, pp. 1005-17, (2000) (PubMed).

Lowry, Rodda, Lightman, Ingram et al.: "Corticotropin-releasing factor increases in vitro firing rates of serotonergic neurons in the rat dorsal raphe nucleus: evidence for activation of a topographically organized mesolimbocortical ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 20, Issue 20, pp. 7728-36, (2000) (PubMed).

Synonyms and alternative names related to Tryptophan Hydroxylase 1

tryptophan hydroxylase 1 (TPH1), tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a (tph1a), TryPtophan Hydroxylase (tph-1), tryptophan hydroxylase 1b (tph1b), tryptophan hydroxylase 1 (Tph1), tryptophan hydroxylase 1 L homeolog (tph1.L), tryptophan hydroxylase 1 (LOAG_02149), tryptophan 5-hydroxylase 1 (Tsp_05203), LOC100229598, SERGEF, tph, Tph, TPH, tph1, tph1l, tph2, tphD1, tphD2, TPRH, TRPH

Protein level used designations for Tryptophan Hydroxylase 1

  • L-tryptophan hydroxylase
  • indoleacetic acid-5-hydroxylase
  • tryptophan 5-hydroxylase 1
  • tryptophan 5-monooxygenase 1
  • tryptophan hydroxylase (tryptophan 5-monooxygenase)
  • tph1-1
  • tryptophan hydroxylase (tryptophan 5-monooxygenase
  • tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)
  • tryptophan 5-hydroxylase 2
  • TryPtophan Hydroxylase family member (tph-1)
  • tph1-2
  • tryptophan hydroxylase 1, like
  • tryptophan hydroxylase 2
  • tryptophan hydroxylase D2
  • tryptophan 5-hydroxylase
  • tryptophan 5-monooxygenase
  • secretion regulating guanine nucleotide exchange factor
  • tryptophan hydroxylase 1
  • tryptophan 5-hydroxylase 1-like
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