SRPK2 产品
(SFRS Protein Kinase 2 (SRPK2))
Categories
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up- regulation. Plays an essential role in splicesomal B complex formation via the phosphorylation of DDX23/PRP28.
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured SRPK2 Categories
Recommended SRPK2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7170677
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN520488
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6265291
Quantity
100 μL
Datasheet
Datasheet
Recommended SRPK2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570616
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
Cat. No.
ABIN5570614
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321346
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SRPK2 Products
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
: "SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells." in: The Journal of cell biology, Vol. 140, Issue 4, pp. 737-50, (1998) (PubMed).
Synonyms and alternative names related to SRPK2
SRSF protein kinase 2 (SRPK2), serine/arginine-rich protein specific kinase 2 (Srpk2), SRSF protein kinase 2 (Srpk2), SRSF protein kinase 2 (srpk2), SRSF protein kinase 2 L homeolog (srpk2.L), AW226533, AW492537, AW547358, mSRPK2, SFRSK2, sfrsk2, srpk2, srpk2-b, srpk2b, Wbp6Protein level used designations for SRPK2
- SFRS protein kinase 2
- SR protein kinase 2
- SR-protein-specific kinase 2
- serine kinase SRPK2
- serine/arginine-rich protein-specific kinase 2
- serine/arginine-rich splicing factor kinase 2
- serine/threonine-protein kinase SRPK2
- SRSF protein kinase 2
- WW domain binding protein 6
- serine/arginine-rich protein specific kinase 2
- serine/threonine-protein kinase SRPK2-like
- SFRS protein kinase 2b
- SRSF protein kinase 2 L homeolog
You are here:
