SRSF2 产品
(serine/arginine-Rich Splicing Factor 2 (SRSF2))
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The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010].
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Featured SRSF2 Categories
SRSF2 抗体
High quality antibodies with extensive validation data.
SRSF2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SRSF2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SRSF2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN1682677
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Pig, Rat, Xenopus laevis
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6753005
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN389301
Quantity
400 μL
Datasheet
Datasheet
Recommended SRSF2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970115
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959386
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1157103
Quantity
96 tests
Datasheet
Datasheet
Recommended SRSF2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319752
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3077330
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3123120
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SRSF2 Products
: "The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation." in: PLoS pathogens, Vol. 15, Issue 10, pp. e1008093, (2019) (PubMed).: "Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization." in: eLife, Vol. 7, (2019) (PubMed).
: "Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2." in: Journal of cell science, Vol. 129, Issue 2, pp. 314-28, (2016) (PubMed).
: "Global variability in gene expression and alternative splicing is modulated by mitochondrial content." in: Genome research, Vol. 25, Issue 5, pp. 633-44, (2015) (PubMed).
: "FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis." in: Cell research, Vol. 24, Issue 12, pp. 1403-19, (2014) (PubMed).
: "Gadd45a is an RNA binding protein and is localized in nuclear speckles." in: PLoS ONE, Vol. 6, Issue 1, pp. e14500, (2011) (PubMed).
: "Vitamin A metabolite, all-trans-retinoic acid, mediates alternative splicing of protein kinase C deltaVIII (PKCdeltaVIII) isoform via splicing factor SC35." in: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 25987-95, (2010) (PubMed).
: "Dephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cgamma governs Cajal body localization and stability of the SMN complex." in: The Journal of cell biology, Vol. 179, Issue 3, pp. 451-65, (2007) (PubMed).
: "A potential molecular mechanism for regulating pre-mRNA splicing of implantation-related genes through unique uterine expression of splicing factor SC35 in women and rhesus monkeys." in: Reproduction (Cambridge, England), Vol. 124, Issue 2, pp. 209-17, (2002) (PubMed).
: "A putative mammalian RNA helicase with an arginine-serine-rich domain colocalizes with a splicing factor." in: The Journal of biological chemistry, Vol. 270, Issue 26, pp. 15702-6, (1995) (PubMed).
Synonyms and alternative names related to SRSF2
serine and arginine rich splicing factor 2 (SRSF2), serine/arginine-rich splicing factor 2 (Srsf2), serine and arginine rich splicing factor 2 (Srsf2), serine/arginine-rich splicing factor 2 L homeolog (srsf2.L), D11Wsu175e, MRF-1, PR264, Pr264, pr264, SC-35, sc-35, SC35, sc35, SFRS2, Sfrs2, sfrs2, SFRS2A, sfrs2a, Sfrs10, SRp30b, srp30bProtein level used designations for SRSF2
- SR splicing factor 2
- splicing component, 35 kDa
- splicing factor SC35
- splicing factor, arginine/serine-rich 2
- myelin regulatory factor 1
- putative myelin regulatory factor 1
- splicing factor Sc35
- splicing factor, arginine/serine-rich 2 (SC-35)
- SC-35
- PR 264 protein
- arginine/serine-rich2 splicing factor
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