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SRD5A3 产品

(Steroid 5 alpha-Reductase 3 (SRD5A3))

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The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011].

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Featured SRD5A3 Categories

SRD5A3 抗体

High quality antibodies with extensive validation data.

SRD5A3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SRD5A3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN651469
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (1)
Cat. No. ABIN5588745
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Guinea Pig, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6738629
Quantity 100 μL
Datasheet Datasheet

Recommended SRD5A3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321304
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3118190
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3120089
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SRD5A3 Products

Castro, Sánchez, Torres, Ortega: "Bisphenol A, bisphenol F and bisphenol S affect differently 5α-reductase expression and dopamine-serotonin systems in the prefrontal cortex of juvenile female rats." in: Environmental research, Vol. 142, pp. 281-7, (2015) (PubMed).

Sánchez, Castro, Torres, Ortega: "Effects of different ethanol-administration regimes on mRNA and protein levels of steroid 5α-reductase isozymes in prefrontal cortex of adolescent male rats." in: Psychopharmacology, Vol. 231, Issue 17, pp. 3273-80, (2014) (PubMed).

Uemura, Tamura, Chung, Honma, Okuyama, Nakamura, Nakagawa: "Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer." in: Cancer science, Vol. 99, Issue 1, pp. 81-6, (2007) (PubMed).

Synonyms and alternative names related to SRD5A3

steroid 5 alpha-reductase 3 (SRD5A3), steroid 5 alpha-reductase 3 (Srd5a3), steroid 5 alpha-reductase 3 S homeolog (srd5a3.S), 1110025P14Rik, A430076C09, AV364670, AW987574, CDG1P, CDG1Q, D730040M03Rik, H5ar, KRIZI, RGD1308828, S5AR 3, SRD5A2L, Srd5a2l, SRD5A2L1, SRD5alpha3

Protein level used designations for SRD5A3

  • 3-oxo-5-alpha-steroid 4-dehydrogenase 3
  • S5AR 3
  • SR type 3
  • polyprenol reductase
  • probable polyprenol reductase
  • H5AR
  • steroid 5 alpha-reductase 2 like
  • steroid 5 alpha-reductase 2-like; H5AR gene; steroid 5 alpha-reductase 2 like
  • steroid 5-alpha-reductase 3
  • Probable polyprenol reductase
  • Steroid 5-alpha-reductase 3
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