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SRCAP 产品

(Snf2-Related CREBBP Activator Protein (SRCAP))

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This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012].

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Featured SRCAP Categories

SRCAP 抗体

High quality antibodies with extensive validation data.

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Latest Publications for our SRCAP Products

Wong, Cox, Chrivia: "The chromatin remodeling protein, SRCAP, is critical for deposition of the histone variant H2A.Z at promoters." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26132-9, (2007) (PubMed).

Synonyms and alternative names related to SRCAP

Snf2 related CREBBP activator protein (SRCAP), Snf2-related CREBBP activator protein (Srcap), B930091H02Rik, D030022P06Rik, DOMO1, EAF1, F630004O05Rik, FLHS, RGD1565642, SWR1

Protein level used designations for SRCAP

  • Snf2-related CBP activator protein
  • Swi2/Snf2-related ATPase homolog, domino homolog 1
  • domino homolog 2
  • helicase SRCAP
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