(serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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Latest Publications for our SPTLC1 Products: "Transcriptional Differences in Lipid-Metabolizing Enzymes in Murine Sebocytes Derived from Sebaceous Glands of the Skin and Preputial Glands." in: International journal of molecular sciences, Vol. 22, Issue 21, (2021) (PubMed).
: "Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells." in: The Journal of biological chemistry, Vol. 290, Issue 1, pp. 90-8, (2015) (PubMed).
: "Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology." in: Biochimica et biophysica acta, Vol. 1791, Issue 8, pp. 746-56, (2009) (PubMed).
: "Apoptotic sphingolipid signaling by ceramides in lung endothelial cells." in: American journal of respiratory cell and molecular biology, Vol. 38, Issue 6, pp. 639-46, (2008) (PubMed).
: "Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis." in: The Journal of investigative dermatology, Vol. 119, Issue 5, pp. 1048-52, (2002) (PubMed).
: "Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I." in: Nature genetics, Vol. 27, Issue 3, pp. 309-12, (2001) (PubMed).
: "Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum." in: Brain research, Vol. 909, Issue 1-2, pp. 187-93, (2001) (PubMed).
: "A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32108-14, (1998) (PubMed).
: "Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis." in: European journal of biochemistry / FEBS, Vol. 249, Issue 1, pp. 239-47, (1997) (PubMed).
Synonyms and alternative names related to SPTLC1serine palmitoyltransferase 1 (SPT1), serine palmitoyltransferase 1 (AFUA_6G00300), Serine palmitoyltransferase 1 (PAS_FragB_0040), serine palmitoyltransferase long chain base subunit 1 (SPTLC1), serine palmitoyltransferase, long chain base subunit 1 (sptlc1), serine palmitoyltransferase, long chain base subunit 1 L homeolog (sptlc1.L), serine palmitoyltransferase, long chain base subunit 1 (Sptlc1), serine palmitoyltransferase long chain base subunit 1 (Sptlc1), Afu6g00300, ATSPT1, AW552086, C77762, E030036H05, HSAN1, HSN1, LBC1, LCB1, Lcb1, RGD1306617, SERINE PALMITOYLTRANSFERASE 1, serine palmitoyltransferase 1, SPT1, Spt1, SPTI, wu:fc75h04, wu:fp41c08, zgc:112247
Protein level used designations for SPTLC1
- Serine palmitoyltransferase 1
- LCB 1
- SPT 1
- long chain base biosynthesis protein 1
- serine C-palmitoyltransferase
- serine palmitoyltransferase 1
- serine-palmitoyl-CoA transferase 1
- serine palmitoyltransferase subunit 1
- Long chain base biosynthesis protein 1
- Serine-palmitoyl-CoA transferase 1
- serine palmitoyltransferase LCB1 subunit