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SPRY4 产品

(Sprouty RTK Signaling Antagonist 4 (SPRY4))

Categories

SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS\; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).[supplied by OMIM, Mar 2008].

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Featured SPRY4 Categories

SPRY4 抗体

High quality antibodies with extensive validation data.

SPRY4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPRY4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN652338
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7251967
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6264444
Quantity 100 μL
Datasheet Datasheet

Recommended SPRY4 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232009
Quantity 96 tests
Datasheet Datasheet

Recommended SPRY4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3119999
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3077322
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321265
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SPRY4 Products

Lee, Park, Kim, Ko, Lee, Kim, Park: "Novel Function of Sprouty4 as a Regulator of Stemness and Differentiation of Embryonic Stem Cells." in: Development & reproduction, Vol. 20, Issue 2, pp. 171-7, (2016) (PubMed).

Taniguchi, Sasaki, Watari, Yasukawa, Imaizumi, Ayada, Okamoto, Ishizaki, Kato, Kohno, Kimura, Sato, Ono, Yonemitsu, Yoshimura: "Suppression of Sproutys has a therapeutic effect for a mouse model of ischemia by enhancing angiogenesis." in: PLoS ONE, Vol. 4, Issue 5, pp. e5467, (2009) (PubMed).

Ding, Bellusci, Shi, Warburton: "Genomic structure and promoter characterization of the human Sprouty4 gene, a novel regulator of lung morphogenesis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 287, Issue 1, pp. L52-9, (2004) (PubMed).

Sasaki, Taketomi, Kato, Saeki, Nonami, Sasaki, Kuriyama, Saito, Shibuya, Yoshimura: "Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1." in: Nature cell biology, Vol. 5, Issue 5, pp. 427-32, (2003) (PubMed).

Leeksma, Van Achterberg, Tsumura, Toshima, Eldering, Kroes, Mellink, Spaargaren, Mizuno, Pannekoek, de Vries: "Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1." in: European journal of biochemistry / FEBS, Vol. 269, Issue 10, pp. 2546-56, (2002) (PubMed).

Synonyms and alternative names related to SPRY4

sprouty RTK signaling antagonist 4 (Spry4), sprouty RTK signaling antagonist 4 (SPRY4), sprouty (Drosophila) homolog 4 (spry4), sprouty homolog 4 (Drosophila) (Spry4), A030006O18Rik, HH17, LOC100218545, sprouty4, SPRY4

Protein level used designations for SPRY4

  • protein sprouty homolog 4
  • sprouty-like protein 4
  • sprouty homolog 4
  • SPRY domain-containing protein 4
  • spry-4
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