SRCAP 抗体 (AA 665-780)
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- 抗原 See all SRCAP 抗体
- SRCAP (Snf2-Related CREBBP Activator Protein (SRCAP))
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抗原表位
- AA 665-780
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRCAP antibody is un-conjugated
- 应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SRCAP
- 亚型
- IgG
- Top Product
- Discover our top product SRCAP Primary Antibody
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anti-Snf2-Related CREBBP Activator Protein (SRCAP) (Internal Region) antibody
Verified SRCAP 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Snf2-Related CREBBP Activator Protein (SRCAP) (AA 309-322) antibodyVerified SRCAP 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SRCAP (Snf2-Related CREBBP Activator Protein (SRCAP))
- 别名
- SRCAP (SRCAP 产品)
- 别名
- DOMO1 antibody, EAF1 antibody, FLHS antibody, SWR1 antibody, B930091H02Rik antibody, D030022P06Rik antibody, F630004O05Rik antibody, RGD1565642 antibody, Snf2 related CREBBP activator protein antibody, Snf2-related CREBBP activator protein antibody, SRCAP antibody, Srcap antibody
- 背景
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Synonyms: DOMO1, EAF1, Helicase SRCAP, Snf2 related CBP activator protein, SWR1, SRCAP_HUMAN.
Background: SRCAP (Snf2-related CREBBP activator protein), also known as EAF1, SWR1, or DOMO1, is a 3,230 amino acid protein that belongs to a family of helicases and contains one HSA domain, one helicase C-terminal domain, one helicase ATP-binding domain and three A.T hook DNA-binding domains. Localized to the nucleus, SRCAP functions as a catalytic component of the SRCAP complex, a multi-protein structure that mediates the ATP-dependent exchange of histone dimers for nucleosomal histones, an event that regulates the transcription of select genes via chromatin remodeling. Additionally, the SRCAP complex acts as a coactivator for steroid receptor-mediated transcription, Notch-mediated transcription and CREB-mediated transcription. SRCAP is expressed as multiple alternatively spliced isoforms and is subject to DNA damage-dependent phosphorylation by ATM or ATR.
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