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SRGAP1 产品

(SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1))

Categories

GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

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Featured SRGAP1 Categories

SRGAP1 抗体

High quality antibodies with extensive validation data.

SRGAP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SRGAP1 抗体

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Reactivity
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Validations
Cat. No.
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Datasheet
Reactivity Human
Application ELISA, WB, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN528215
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN566130
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
  • (3)
Cat. No. ABIN7192644
Quantity 100 μL
Datasheet Datasheet

Recommended SRGAP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6201282
Quantity 96 tests
Datasheet Datasheet

Recommended SRGAP1 蛋白

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Reactivity
Source
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Cat. No.
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1321316
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095688
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
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Cat. No. ABIN3136842
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SRGAP1 Products

Fan, Yang, Kumar, Tumelty, Pisarek-Horowitz, Rasouly, Sharma, Chan, Tyminski, Shamashkin, Belghasem, Henderson, Coyle, Salant, Berasi, Lu: "SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion." in: JCI insight, Vol. 1, Issue 19, pp. e86934, (2016) (PubMed).

Hwang, Kohl, Fan, Vivante, Chan, Dworschak, Schulz, van Eerde, Hilger, Gee, Pennimpede, Herrmann, van de Hoek, Renkema, Schell, Huber, Reutter, Soliman, Stajic, Bogdanovic, Kehinde, Lifton, Tasic, Lu et al.: "Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract. ..." in: Human genetics, Vol. 134, Issue 8, pp. 905-16, (2015) (PubMed).

Dai, Ma, Chen, Mi, Fu, Cui, Jin: "A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1." in: Molecular and cellular neurosciences, Vol. 60, pp. 10-25, (2014) (PubMed).

He, Bronisz, Liyanarachchi, Nagy, Li, Huang, Akagi, Saji, Kula, Wojcicka, Sebastian, Wen, Puch, Kalemba, Stachlewska, Czetwertynska, Dlugosinska, Dymecka, Ploski, Krawczyk, Morrison, Ringel, Kloos et al.: "SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility. ..." in: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 5, pp. E973-80, (2013) (PubMed).

Yasuda, Theodorakis, Subramanian, Chinnadurai: "Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence." in: The Journal of biological chemistry, Vol. 273, Issue 20, pp. 12415-21, (1998) (PubMed).

Synonyms and alternative names related to SRGAP1

SLIT-ROBO Rho GTPase activating protein 1 (SRGAP1), SLIT-ROBO Rho GTPase activating protein 1 (srgap1), SLIT-ROBO Rho GTPase activating protein 1 (Srgap1), 4930572H05Rik, ARHGAP13, Arhgap13, RGD1566260

Protein level used designations for SRGAP1

  • SLIT-ROBO Rho GTPase-activating protein 1
  • SLIT-ROBO Rho GTPase activating protein 1
  • SLIT-ROBO Rho GTPase-activating protein 1-like
  • rho GTPase-activating protein 13
  • Rho GTPase activating protein 13
  • Rho GTPase activating protein
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