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- 抗原 See all SRGAP1 抗体
- SRGAP1 (SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRGAP1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of Human SRGAP1
- 亚型
- IgG
- Top Product
- Discover our top product SRGAP1 Primary Antibody
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anti-SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1) (AA 952-1050) antibody
SRGAP1 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 5D10 unconjugated
anti-SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1) (AA 952-1050) antibodySRGAP1 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 5D2 unconjugated
anti-SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1) (AA 1-1085) antibodySRGAP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1) (AA 673-720) antibodySRGAP1 适用: 人, 小鼠, Cow, 大鼠, 犬, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1) (AA 136-192) antibodySRGAP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SRGAP1 (SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1))
- 别名
- SRGAP1 (SRGAP1 产品)
- 别名
- ARHGAP13 antibody, 4930572H05Rik antibody, Arhgap13 antibody, RGD1566260 antibody, SLIT-ROBO Rho GTPase activating protein 1 antibody, SRGAP1 antibody, srgap1 antibody, Srgap1 antibody
- 背景
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Background: SRGAP1 contains an FCH (Fes/CIP4 homology) domain, a Rho-GAP domain and an SH3 domain. In the presence of Slit, SRGAP1 (via its SH3 domain) binds to the CC3 motif in robo (a protein responsible for mediating the repulsive effect of Slit) with higher affinity and inhibits Cdc42 activity in a robo/SRGAP-dependent manner. More specifically, SRGAP1 increases the intrinsic GTPase activity of Cdc42, thereby converting it to its inactive, GDP-bound form. Inactivation of Cdc42 µLtimately leads to a decrease in actin polymerization.
Aliases: 4930572H05Rik antibody, ARHGAP13 antibody, FLJ22166 antibody, KIAA1304 antibody, RGD1566260 antibody, Rho GTPase activating protein 13 antibody, Rho GTPase-activating protein 13 antibody, SLIT ROBO Rho GTPase activating protein 1 antibody, SLIT-ROBO Rho GTPase-activating protein 1 antibody, SRGAP 1 antibody, srGAP1 antibody, SRGP1_HUMAN antibody
- UniProt
- Q7Z6B7
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