SETD7 抗体
(SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
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81 results
SETD7
适用: 人, 小鼠
WB, IHC (p)
宿主: 兔
Polyclonal
RB2763
unconjugated
SETD7
适用: 人
WB, ELISA, FACS, IF, ICC
宿主: 小鼠
Monoclonal
s4E5
unconjugated
SETD7
适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Cow, 斑马鱼, 猴, Bat
WB
宿主: 兔
Polyclonal
unconjugated
1 image
SETD7
适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Cow, 斑马鱼, 豚鼠
WB
宿主: 兔
Polyclonal
unconjugated
1 image
1 reference
SETD7
适用: 人
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
SETD7
适用: 人
WB, FACS, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
Latest Publications for our SETD7 抗体
: "Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial." in: Theranostics, Vol. 10, Issue 8, pp. 3533-3545, (2021) (PubMed).: "Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds." in: Acta biomaterialia, Vol. 73, pp. 522-530, (2018) (PubMed).
: "Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase." in: Molecular cell, Vol. 30, Issue 3, pp. 336-47, (2008) (PubMed).
: "Protein demethylation required for DNA methylation." in: Nature genetics, Vol. 41, Issue 1, pp. 10-1, (2008) (PubMed).
: "The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 26, pp. 10835-40, (2007) (PubMed).
: "Regulation of p53 activity through lysine methylation." in: Nature, Vol. 432, Issue 7015, pp. 353-60, (2004) (PubMed).
: "Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet." in: The EMBO journal, Vol. 22, Issue 2, pp. 292-303, (2003) (PubMed).
: "Structure and catalytic mechanism of the human histone methyltransferase SET7/9." in: Nature, Vol. 421, Issue 6923, pp. 652-6, (2003) (PubMed).
: "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1." in: Genes & development, Vol. 17, Issue 7, pp. 896-911, (2003) (PubMed).
Aliases for SETD7 抗体
SET domain containing lysine methyltransferase 7 (SETD7) 抗体SET domain containing (lysine methyltransferase) 7 (setd7) 抗体
SET domain containing (lysine methyltransferase) 7 (Setd7) 抗体
1600028F23Rik 抗体
H3K4MT 抗体
KMT7 抗体
mKIAA1717 抗体
SET7 抗体
set7 抗体
Set7 抗体
SET7/9 抗体
Set7/9 抗体
SET9 抗体
zgc:92330 抗体
zgc:101860 抗体
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