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SETD2 抗体

(SET Domain Containing 2 (SETD2))
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008].
SETD2 抗体  (AA 803-1103) SETD2 抗体  (AA 803-1103) SETD2 抗体 (AA 803-1103) (ABIN1682666)

SETD2 适用: 人 IF, WB 宿主: 兔 Polyclonal unconjugated

SETD2 抗体  (N-Term) SETD2 抗体  (N-Term) SETD2 抗体 (N-Term) (ABIN2783051)

SETD2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马 IHC, WB 宿主: 兔 Polyclonal unconjugated

SETD2 抗体  (Internal Region) SETD2 抗体  (Internal Region) SETD2 抗体 (Internal Region) (ABIN238587)

Verified SETD2 适用: 人 ELISA, FACS 宿主: 山羊 Polyclonal unconjugated

SETD2 抗体 by Grade

Find SETD2 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SETD2 抗体 by 适用

Find SETD2 抗体 for a variety of species such as anti-Human SETD2, anti-Mouse SETD2, anti-Rat SETD2. The species listed below are among those available. Click on a link to go to the corresponding products.

SETD2 抗体 by 应用范围

Find SETD2 抗体 validated for a specific application such as ELISA, WB, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SETD2 抗体 by 抗体来源

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SETD2 抗体 by 抗原表位

Find SETD2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SETD2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SETD2 抗体. Click on a link to go to the corresponding products.

SETD2 抗体 by 克隆

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SETD2 抗体 by 标记

Find SETD2 抗体 with a specific conjugate such as Biotin, APC, Alkaline Phosphatase (AP). The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SETD2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Rat
Application IHC, WB
Validations
  • (3)
Cat. No. ABIN925965
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7131042
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN6265018
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Rat
Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN321311
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (1)
Cat. No. ABIN6242388
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF, IHC, WB
Validations
Cat. No. ABIN7118991
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, WB
Validations
Cat. No. ABIN7193416
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
Cat. No. ABIN7235965
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
Cat. No. ABIN2443213
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IC, IF, IP, WB
Validations
Cat. No. ABIN5661698
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6812968
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6885347
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6829031
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6845094
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6901410
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SETD2 抗体

Jia, Miron, Yin, Xu, Luo, Wang, Jia, Wu, Zhang, Li: "HnRNPL inhibits the osteogenic differentiation of PDLCs stimulated by SrCl2 through repressing Setd2." in: Journal of cellular and molecular medicine, Vol. 23, Issue 4, pp. 2667-2677, (2020) (PubMed).

Huang, Gu, Li: "H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation." in: The Journal of biological chemistry, Vol. 293, Issue 20, pp. 7811-7823, (2019) (PubMed).

Jia, Long, Miron, Yin, Wei, Zhang, Wu: "Setd2 is associated with strontium-induced bone regeneration." in: Acta biomaterialia, Vol. 53, pp. 495-505, (2018) (PubMed).

Chen, Liu, Liu, Xia, Zhang, Han, Jiang, Wang, Cao: "Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity." in: Cell, Vol. 170, Issue 3, pp. 492-506.e14, (2017) (PubMed).

Zhu, Lei, Ju, Wang, Huang, Yang, Shao, Zhu, Wei, Fu, Li, Wu: "SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing." in: Nucleic acids research, Vol. 45, Issue 1, pp. 92-105, (2017) (PubMed).

Yi, Tao, Lin, Dai, Yang, Yue, Jiang, Li, Jiang, Andrade, Chang: "Histone methyltransferase Setd2 is critical for the proliferation and differentiation of myoblasts." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 4, pp. 697-707, (2017) (PubMed).

Kanu, Grönroos, Martinez, Burrell, Yi Goh, Bartkova, Maya-Mendoza, Mistrík, Rowan, Patel, Rabinowitz, East, Wilson, Santos, McGranahan, Gulati, Gerlinger, Birkbak, Joshi, Alexandrov, Stratton, Powles et al.: "SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. ..." in: Oncogene, Vol. 34, Issue 46, pp. 5699-708, (2015) (PubMed).

Barrand, Andersen, Collas: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." in: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).

Müller, Rieder, Karpova, John, Trajanoski, McNally: "Organization of chromatin and histone modifications at a transcription site." in: The Journal of cell biology, Vol. 177, Issue 6, pp. 957-67, (2007) (PubMed).

Sun, Wei, Wu, Hu, Wang, Wang, Zhang, Chen, Huang, Chen: "Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase." in: The Journal of biological chemistry, Vol. 280, Issue 42, pp. 35261-71, (2005) (PubMed).

Aliases for SETD2 抗体

SET domain containing 2 (Setd2) 抗体
SET domain containing 2 (SETD2) 抗体
HBP231 抗体
HIF-1 抗体
HIP-1 抗体
HYPB 抗体
Kif9 抗体
KMT3A 抗体
p231HBP 抗体
SET2 抗体
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