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SETD7 抗体

SETD7 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7270261
发货至: 中国
  • 抗原 See all SETD7 抗体
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    适用
    • 63
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    宿主
    • 53
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    • 1
    克隆类型
    • 52
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    单克隆
    标记
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    This SETD7 antibody is un-conjugated
    应用范围
    • 54
    • 28
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    Western Blotting (WB)
    原理
    SETD7 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human SETD7
    亚型
    IgG
    Top Product
    Discover our top product SETD7 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    别名
    SETD7 (SETD7 产品)
    别名
    KMT7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, set7 antibody, zgc:101860 antibody, zgc:92330 antibody, 1600028F23Rik antibody, H3K4MT antibody, Set7 antibody, Set7/9 antibody, mKIAA1717 antibody, SET domain containing lysine methyltransferase 7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SETD7 antibody, setd7 antibody, Setd7 antibody
    背景
    Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.,KMT7, SET7, SET7/9, SET9,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Methylation,Epigenetics & Nuclear Signaling,SETD7
    分子量
    41kDa
    基因ID
    80854
    UniProt
    Q8WTS6
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