Septin 2 抗体
(Septin 2 (SEPT2))
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes (By similarity).
recommended
Verified SEPT2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
recommended
recommended
Septin 2 抗体 by Grade
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Septin 2 抗体 by 应用范围
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Septin 2 抗体 by 克隆形成能力
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Septin 2 抗体 by 克隆
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Popular Septin 2 抗体
Product
Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Application
WB, ELISA, IHC
Validations
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Cat. No.
ABIN308439
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IF
Validations
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Cat. No.
ABIN518271
Quantity
50 μg
Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC
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Cat. No.
ABIN7168865
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
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Cat. No.
ABIN6257343
Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
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Cat. No.
ABIN7244000
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
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Cat. No.
ABIN6147552
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
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Cat. No.
ABIN2854352
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IF
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Cat. No.
ABIN7261748
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
- (1)
Cat. No.
ABIN518272
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Dog, Human, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6744094
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6741393
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN1537024
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN720206
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN720208
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our Septin 2 抗体
: "Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins." in: Oncotarget, Vol. 10, Issue 31, pp. 2959-2972, (2019) (PubMed).: "Septins arrange F-actin-containing fibers on the Chlamydia trachomatis inclusion and are required for normal release of the inclusion by extrusion." in: mBio, Vol. 5, Issue 5, pp. e01802-14, (2014) (PubMed).
: "Modulation of septin and molecular motor recruitment in the microtubule environment of the Taxol-resistant human breast cancer cell line MDA-MB-231." in: Proteomics, Vol. 11, Issue 19, pp. 3877-86, (2011) (PubMed).
: "Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7." in: Cell, Vol. 130, Issue 5, pp. 837-50, (2007) (PubMed).
Aliases for Septin 2 抗体
septin 2 (SEPT2) 抗体septin 2 (Sept2) 抗体
septin 2 (sept2) 抗体
septin 2 L homeolog (sept2.L) 抗体
septin 2-like (SEPT2L) 抗体
COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain (sepT2) 抗体
septin 2 S homeolog (sept2.S) 抗体
AW208991 抗体
DIFF6 抗体
diff6 抗体
hNedd5 抗体
hnedd5 抗体
mKIAA0158 抗体
Nedd-5 抗体
NEDD5 抗体
Nedd5 抗体
nedd5 抗体
Pnutl3 抗体
pnutl3 抗体
Sep-02 抗体
sept2 抗体
SEPT2 抗体
sept2-B 抗体
septa 抗体
Septin-2 抗体
Septin-2A 抗体
Septin-2B 抗体
Septin-A 抗体
Vesp11 抗体
wu:fb52g01 抗体
wu:fb99a01 抗体
xlsepta 抗体
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