(SUMO/sentrin Specific Peptidase Family Member 8 (SENP8))
This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009].
Ehrentraut, Kominsky, Glover, Campbell, Kelly, Bowers, Bayless, Colgan: "Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 1, pp. 392-400, (2012) (PubMed).
Mendoza, Shen, Botting, Lewis, Chen, Ink, Hay: "NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 25637-43, (2003) (PubMed).
Gan-Erdene, Nagamalleswari, Yin, Wu, Pan, Wilkinson: "Identification and characterization of DEN1, a deneddylase of the ULP family." in: The Journal of biological chemistry, Vol. 278, Issue 31, pp. 28892-900, (2003) (PubMed).
Wu, Yamoah, Dolios, Gan-Erdene, Tan, Chen, Lee, Wei, Wilkinson, Wang, Pan: "DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1." in: The Journal of biological chemistry, Vol. 278, Issue 31, pp. 28882-91, (2003) (PubMed).
Aliases for SENP8 抗体
SUMO/sentrin peptidase family member, NEDD8 specific L homeolog (senp8.L) 抗体 Cysteine proteinases superfamily protein (AT5G60190) 抗体 SUMO/sentrin specific peptidase 8 (Senp8) 抗体 SUMO/sentrin peptidase family member, NEDD8 specific (SENP8) 抗体 SUMO/sentrin peptidase family member, NEDD8 specific (Senp8) 抗体 9130010J17Rik 抗体 AU020827 抗体 den1 抗体 Den1 抗体 DEN1 抗体 F15L12.8 抗体 F15L12_8 抗体 MGC84956 抗体 nedp1 抗体 Nedp1 抗体 NEDP1 抗体 prsc2 抗体 Prsc2 抗体 PRSC2 抗体