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Human GEMIN5 Protein expressed in HEK-293 Cells - ABIN2721790
Francisco-Velilla, Fernandez-Chamorro, Ramajo, Martinez-Salas: The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation. in Nucleic acids research 2016
This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
gem-associated protein 5