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GEMIN5 Protein (Myc-DYKDDDDK Tag)

GEMIN5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2721790
发货至: 中国
  • 抗原 See all GEMIN5 蛋白
    GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
    蛋白类型
    Recombinant
    宿主
    • 2
    • 1
    资源
    • 2
    • 1
    HEK-293 Cells
    标记
    This GEMIN5 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Gemin-5 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GEMIN5 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Francisco-Velilla, Fernandez-Chamorro, Ramajo, Martinez-Salas: "The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation." in: Nucleic acids research, Vol. 44, Issue 17, pp. 8335-51, (2016) (PubMed).

  • 抗原
    GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
    别名
    Gemin-5 (GEMIN5 产品)
    别名
    GEMIN-5 Protein, AA407055 Protein, AA407208 Protein, AI451603 Protein, BB194447 Protein, C330013N08 Protein, gem nuclear organelle associated protein 5 Protein, gem (nuclear organelle) associated protein 5 Protein, GEMIN5 Protein, Gemin5 Protein
    背景
    This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
    分子量
    168.4 kDa
    NCBI登录号
    NP_056280
    途径
    Ribonucleoprotein Complex Subunit Organization
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