GDNF 蛋白
(Glial Cell Line Derived Neurotrophic Factor (GDNF))
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| GDNF Protein (Biotin) | 人 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 78-211) (Fc Tag) | 人 | HEK-293 Cells |
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| GDNF Protein (AA 78-211) (His-IF2DI Tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 78-211) (His-IF2DI Tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 1-211) (GST tag) | 人 | 小麦胚 |
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| GDNF Protein (SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 29-258) (His tag) | 猕猴 | 人细胞 |
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| GDNF Protein (AA 78-211) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 77-211) | 小鼠 | CHO Cells |
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| GDNF Protein (AA 109-211) (His tag) | 人 | Baculovirus infected Insect Cells |
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| GDNF Protein (AA 78-211) | 人 | 大肠杆菌（E. Coli） |
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| GDNF Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GDNF Protein (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 79-217) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 78-211) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 78-211) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 109-211) (TRX tag) | 人 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 109-211) (Fc Tag) | 人 | Mammalian Cells |
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| GDNF Protein (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GDNF Protein (AA 78-211) (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- FACS (Flow Cytometry: 有验证图片)
- LCI (Live Cell Imaging: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- FW (Fluorescene Western: 有验证图片)
- WB (Western Blotting: 所列应用)
- CC (Cell Culture: 所列应用)
- FM (Fluorescence Microscopy: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- 宿主
- 猕猴
- 宿主
- 人细胞
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- 宿主
- 小鼠
- 宿主
- CHO Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 所列应用)
- AcA (Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >95 %
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >98 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 80 %
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 98 % as determined by reducing SDS-PAGE.
Protein
- CC (Cell Culture: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Latest Publications for our GDNF 蛋白
: "A bioenergetic shift is required for spermatogonial differentiation." in: Cell discovery, Vol. 6, pp. 56, (2020) (PubMed).
: "The morphological and molecular changes of brain cells exposed to direct current electric field stimulation." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 18, Issue 5, (2015) (PubMed).
: "Multiple astrocyte transcripts encode nigral trophic factors in rat and human." in: Experimental neurology, Vol. 130, Issue 2, pp. 387-93, (1995) (PubMed).
: "GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons." in: Science (New York, N.Y.), Vol. 260, Issue 5111, pp. 1130-2, (1993) (PubMed).
: "The morphological and molecular changes of brain cells exposed to direct current electric field stimulation." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 18, Issue 5, (2015) (PubMed).
: "Multiple astrocyte transcripts encode nigral trophic factors in rat and human." in: Experimental neurology, Vol. 130, Issue 2, pp. 387-93, (1995) (PubMed).
: "GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons." in: Science (New York, N.Y.), Vol. 260, Issue 5111, pp. 1130-2, (1993) (PubMed).
Aliases for GDNF 蛋白
glial cell derived neurotrophic factor (Gdnf) 蛋白glial cell derived neurotrophic factor a (gdnfa) 蛋白
glial cell derived neurotrophic factor (GDNF) 蛋白
glial cell line derived neurotrophic factor (Gdnf) 蛋白
glial cell derived neurotrophic factor L homeolog (gdnf.L) 蛋白
AI385739 蛋白
ATF1 蛋白
ATF2 蛋白
gdnf 蛋白
GDNF 蛋白
gdnfa 蛋白
hfb1-gdnf 蛋白
HFB1-GDNF 蛋白
HSCR3 蛋白
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